Evidence map›Paper›PMID 29729303›Full record

ArticleThe Journal of allergy and clinical immunology2018

Intestinal microbial-derived sphingolipids are inversely associated with childhood food allergy.

Kathleen Lee-Sarwar, Rachel S Kelly, Jessica Lasky-Su, D Branch Moody, Alex R Mola, Tan-Yun Cheng, Laurie E Comstock, Robert S Zeiger, George T O'Connor, Megan T Sandel and 9 more

Abstract readLetter
In one paragraph

Article in The Journal of allergy and clinical immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 56 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Immunomodulatory metabolites in IgE-mediated food allergy and oral immunotherapy outcomes based on metabolomic profiling.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2024
    Article
  7. Article
  8. Age-specific Metabolomic profiles in children with food allergy.Clinical immunology (Orlando, Fla.) · 2024
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Advancing Food Allergy Through Omics Sciences.The journal of allergy and clinical immunology. In practice · 2021
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 1 country.

Kathleen Lee-SarwarDivision of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass. Electronic address: klee-sarwar@partners.org.
Rachel S KellyChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
Jessica Lasky-SuChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
D Branch MoodyDivision of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
Alex R MolaDivision of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
Tan-Yun ChengDivision of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
Laurie E ComstockDivision of Infectious Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
Robert S ZeigerKaiser Permanente Southern California, San Diego, Calif.
George T O'ConnorPulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, Mass.
Megan T SandelDepartment of Pediatrics, Boston Medical Center, Boston, Mass.
Leonard B BacharierDivision of Pediatric Allergy, Immunology and Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine and St Louis Children's Hospital, St Louis, Mo.
Avraham BeigelmanDivision of Pediatric Allergy, Immunology and Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine and St Louis Children's Hospital, St Louis, Mo.
Nancy LaranjoChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
Diane R GoldChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass; the Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Mass.
Supinda BunyavanichDepartment of Pediatrics - Allergy/Immunology and Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY.
Jessica H SavageDivision of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
Scott T WeissChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
Patrick J BrennanDivision of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
Augusto A LitonjuaChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass. Electronic address: augusto_litonjua@urmc.rochester.edu.
Harvard University · USBrigham and Women's Hospital · USSt. Louis Children's Hospital · USBoston Medical Center · USBoston University · USIcahn School of Medicine at Mount Sinai · USKaiser Permanente · US

Funding

SYSTEMS APPROACHES TO THE EPIDEMIOLOGY, GENETICS AND GENOMICS OF LUNG DISEASEST32HL007427 · NHLBI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI DAWN L DEMEO, Edwin K Silverman · 1985 to 2026
$13.6M
Multi-omic approaches to mechanisms of vitamin D, environmental influences, and the microbiome on asthmaUH3OD023268 · OD · BRIGHAM AND WOMEN'S HOSPITAL · PI LITONJUA, AUGUSTO A, WEISS, SCOTT T · 2018 to 2022
$13.5M
IMMUNOLOGIC BASIS OF RESISTANCE AND HYPERSENSITIVITYT32AI007306 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI Nora Amanda Barrett, Joshua A Boyce · 1985 to 2026
$12.2M
Randomized Trial: Maternal Vitamin D Supplementation to Prevent Childhood AsthmaU01HL091528 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LITONJUA, AUGUSTO A, WEISS, SCOTT T · 2009 to 2013
$10.0M
CD1 Presentation of Self Lipids to Human T CellsR01AR048632 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI MOODY, DAVID BRANCH · 2002 to 2024
$9.4M
RANDOMIZED CONTROLLED TRIAL: VDAART CONTINUATION STUDY - DCC - LEADR01HL091528 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LITONJUA, AUGUSTO A, WEISS, SCOTT T · 2014 to 2018
$9.1M
Nasal biomarkers of asthmaR01AI118833 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BUNYAVANICH, SUPINDA · 2015 to 2019
$3.8M
VDAART FLORA ANCILLARY STUDYR01HL108818 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLD, DIANE R · 2011 to 2013
$1.3M
CD1 autoreactive T cells in human inflammatory skin diseaseR37AR048632 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI DAVID Branch MOODY · 2025 to 2026
$1.1M
Self and dietary lipid antigens for invariant natural killer T cellsK08AI102945 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI BRENNAN, PATRICK JOSEPH · 2013 to 2016
$736k
NHLBI NIH HHS R01 HL091528NHLBI NIH HHS R01 HL108818NHLBI NIH HHS T32 HL007427NHLBI NIH HHS U01 HL091528NIAID NIH HHS K08 AI102945NIAID NIH HHS R01 AI118833NIAID NIH HHS T32 AI007306NIAMS NIH HHS R01 AR048632NIAMS NIH HHS R37 AR048632NIH HHS UH3 OD023268
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacteroides fragilisChild, PreschoolFemaleFood HypersensitivityGastrointestinal MicrobiomeHumansInfantMaleNatural Killer T-CellsSphingolipidsSphingolipids

Identifiers

PMID29729303
PMCPMC6433125
OpenAlexW2799444547

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.