Evidence map›Paper›PMID 29729278›Full record

Trial reportNeuropsychologia2018

Restoration of sensory input may improve cognitive and neural function.

Hanin Karawani, Kimberly Jenkins, Samira Anderson

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Neuropsychologia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06495268 (Healthy Hearing for Healthy Ageing), which is not on this map. Cited by 37 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 8 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06495268 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Healthy Hearing for Healthy Ageing: a Proof-of-concept Randomized Controlled Trial of Data-driven Hearing Rehabilitation Versus Standard Care in Older Adults With Hearing Impairment.

TypeinterventionalSponsorKuopio University HospitalRan2024 to 2028Enrolled200ConditionsSensorineural Hearing Loss, Cognitive DeclineArmsIndividualised data-driven hearing rehabilitation, Standard care hearing rehabilitation
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 8 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Hearing aids for mild to moderate hearing loss in adults.The Cochrane database of systematic reviews · 2026
    Pooled it
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  7. Hearing loss and dementia: radiologic and biomolecular basis of their shared characteristics. A systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Pooled it
  8. Pooled it
  9. Trial
  10. Article
  11. Preoperative Hearing Aids Improve Outcomes of Cochlear Implantation.Clinical and experimental otorhinolaryngology · 2026
    Article
  12. Article
  13. Aging in the Primary Auditory Cortex.Journal of the Association for Research in Otolaryngology : JARO · 2026
    Review
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Hanin KarawaniDepartment of Hearing and Speech Sciences, University of Maryland, College Park, MD 20742, USA. Electronic address: karawani@umd.edu.
Kimberly JenkinsWalter Reed National Military Medical Center, 4494 North Palmer Road, Bethesda, MD 20889, USA. Electronic address: jenkins.ka411@gmail.com.
Samira AndersonDepartment of Hearing and Speech Sciences, University of Maryland, College Park, MD 20742, USA; Neuroscience and Cognitive Science Program, University of Maryland, College Park, MD 20742, USA. Electronic address: sander22@umd.edu.
University of Maryland, College Park · USWalter Reed National Military Medical Center · US

Funding

Age-related changes in neural encoding and perception of temporal speech cuesR21DC015843 · NIDCD · UNIV OF MARYLAND, COLLEGE PARK · PI ANDERSON, SAMIRA B · 2016 to 2018
$436k
NIDCD NIH HHS R21 DC015843
6 · The paper itself

Abstract

Age-related hearing loss is one of the most prevalent health conditions among the elderly. Hearing loss may lead to social isolation, depression, and cognitive decline in older adults. The mechanistic basis for the association between hearing loss and decreased cognitive function remains unknown as does the potential for improving cognition through hearing rehabilitation. To that end, we asked whether the restoration of sensory input through the use of hearing aids would improve cognitive and auditory neural function. We compared a group of first-time hearing aid users with a hearing-matched control group after a period of six months. The use of hearing aids enhanced working memory performance and increased cortical response amplitudes. Neurophysiologic changes correlated with working memory changes, suggesting a mechanism for decreased cognitive function with hearing loss. These results suggest a neural mechanism for the sensory-cognitive connection and underscore the importance of providing auditory rehabilitation for individuals with age-related hearing loss to improve cognitive and neural function. Our findings of improved cognitive function with hearing aid use may lead to increased adoption of hearing loss remedies.

Indexed as

Acoustic StimulationAgedAged, 80 and overAnalysis of VarianceCerebral CortexCognitive AgingElectroencephalographyEvoked Potentials, AuditoryFemaleHearing AidsHearing LossHumansMaleMemory, Short-TermMiddle AgedNeuropsychological TestsAge-related hearing lossAmplificationCortical auditory evoked potentialsHearing aidsHearing lossOlder adults

Identifiers

PMID29729278
PMCPMC5988995
OpenAlexW2800035475

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.