Evidence map›Paper›PMID 29729052›Full record

ArticleDiabetic medicine : a journal of the British Diabetic Association2018

Cardiovascular risk factors in adolescents with prediabetes.

S S Casagrande, A Menke, B Linder, S K Osganian, C C Cowie

Abstract read
In one paragraph

Article in Diabetic medicine : a journal of the British Diabetic Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Prediabetes in Adolescents: Prevalence, Management and Diabetes Prevention Strategies.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021
    Review
  9. Article
  10. Article
  11. Article
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  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

S S CasagrandeSocial & Scientific Systems, Inc., Silver Spring, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-6293-383X
A MenkeSocial & Scientific Systems, Inc., Silver Spring, Bethesda, MD, USA.
B LinderNational Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, USA.
S K OsganianNational Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, USA.
C C CowieNational Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, USA.
National Institute of Diabetes and Digestive and Kidney Diseases · USSocial and Scientific Systems (United States) · US

Funding

Intramural NIH HHS Z99 DK999999
6 · The paper itself

Abstract

aimsAdolescents with Type 2 diabetes are more likely to have cardiovascular disease (CVD) risk factors but there are few data available among adolescents with prediabetes. We characterized CVD risk factors among adolescents with prediabetes in the USA and compared levels of those risk factors with adolescents with normal glucose.

methodsThe 2005-2014 National Health and Nutrition Examination Survey, a nationally representative cross-sectional survey, included 2843 adolescents aged 12-19 years after excluding those with diabetes. Prediabetes was based on an HbA

resultsThe weighted prevalence of prediabetes was 17.4%. After adjustment, prediabetes (vs. normal glucose) was associated with obesity (OR 1.86, 95% CI 1.35-2.55), low HDL-cholesterol (OR 1.62, 95% CI 1.08-2.44), high triglycerides (OR 1.61, 95% CI 1.12-2.30) and elevated liver transaminase (OR 2.09, 95% CI 1.19-3.67), but not with hypertension (OR 1.77, 95% CI 0.88-3.54), elevated total cholesterol (OR 1.30, 95% CI 0.82-2.06), elevated LDL-cholesterol (OR 1.59, 95% CI 0.88-2.88) or albuminuria (OR 1.24, 95% CI 0.76-2.02).

conclusionsUS adolescents with prediabetes are more likely to have obesity, low HDL-cholesterol, high triglycerides and elevated liver transaminase than adolescents with normal glucose. Addressing prediabetes in youth is important for the prevention of Type 2 diabetes and long-term comorbidity.

Identifiers

PMID29729052
PMCPMC6218322
OpenAlexW2801822841

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.