ArticleInternational urology and nephrology2018
Increased risk of kidney damage among Chinese adults with simple renal cyst.
Article in International urology and nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Aspiration-sclerotherapy versus laparoscopic de-roofing in the treatment of renal cysts: which is better?BMC nephrology · 2020Pooled it
- Association between renal function and simple renal cyst growth: a retrospective study.European journal of medical research · 2025Article
- Ultrasonography-guided aspiration and sclerotherapy for simple renal cysts in children: a comparative study with laparoscopic deroofing and optimization of therapeutic approaches.Pediatric surgery international · 2025Article
- Multiple and large simple renal cysts are associated with glomerular filtration rate decline: a cross-sectional study of Chinese population.European journal of medical research · 2024Article
- Decline in measured glomerular filtration rate is associated with simple renal cyst in Chinese patients with type 2 diabetes.Journal of diabetes investigation · 2024Article
- Prevalence, risk factors and clinical characteristics of renal dysfunction in Chinese outpatients with growth simple renal cysts.International urology and nephrology · 2022Article
- Simple renal cyst as an independent risk factor for hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Association of simple renal cysts with metabolic syndrome in adults.Frontiers in public health · 2022Article
- Relationship Between Sporadic Renal Cysts and Renal Function Detected by Isotope Renography in Type 2 Diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- Does the Simple Renal Cyst Treatment Improve Renal Function: A Pilot Study.Advanced biomedical research · 2022Article
- Long-term renal function in living kidney donors with simple renal cysts: A retrospective cohort study.Clinical transplantation · 2020Article
- A 30% incidence of renal cysts with varying sizes and densities in biomedical research swine is not associated with renal dysfunction.Animal models and experimental medicine · 2020Article
- The Relationship Between Simple Renal Cysts and Renal Function in Patients With Type 2 Diabetes.Frontiers in physiology · 2020Article
- Association between simple renal cyst and kidney damage in a Chinese cohort study.Renal failure · 2019Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe presence of simple renal cyst (SRC) has been related to hypertension, the early and long-term allograft function, and aortic disease, but the relationship with kidney damage was still controversial. Accordingly, we conducted a large sample cross-sectional study to explore the association of SRC with indicators of kidney damage among Chinese adults.
methodsA total of 42,369 adults (aged 45.8 ± 13.67 years, 70.6% males) who visited the Health Checkup Clinic were consecutively enrolled. SRC was assessed by ultrasonography according to Bosniak category. Multiple regression models were applied to explore the relationships between SRC and indicators of kidney damage [proteinuria (dipstick urine protein ≥ 1+) and decreased estimated glomerular filtration rate (DeGFR) < 60 ml/min/1.73 m
resultsAmong all participants in the study, the prevalence of SRC was 10.5%. As a categorical outcome, participants with more 1 cyst and with 1 cyst had higher percentage of proteinuria [53 (5.3%) and 93 (2.7%) vs. 596 (1.6%), p < 0.001] and DeGFR [57 (5.7%) and 85 (2.5%) vs. 278 (0.7%), p < 0.001] compared with participants with no cyst. SRC significantly correlated with proteinuria [OR 1.59 (95% CI 1.30-1.95)] and DeGFR [OR 1.97 (95% CI 1.56-2.47)] after adjusting for potential confounders. Furthermore, the results also demonstrated that maximum diameter (per 1 cm increase), bilateral location, and multiple cysts significantly correlated with DeGFR in the multiple logistic regression analysis.
conclusionsThe study revealed that SRC significantly correlated with kidney damage and special attention should be paid among Chinese adults with SRC.
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