Evidence map›Paper›PMID 29728980›Full record

ArticleBiomolecular NMR assignments2018

Backbone resonance assignments of complexes of apo human calmodulin bound to IQ motif peptides of voltage-dependent sodium channels Na

Holly M Isbell, Adina M Kilpatrick, Zesen Lin, Ryan Mahling, Madeline A Shea

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecular NMR assignments, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Feedback contributions to excitation-contraction coupling in native functioning striated muscle.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  2. NaStructure (London, England : 1993) · 2021
    Article
  3. Calmodulin Interactions with Voltage-Gated Sodium Channels.International journal of molecular sciences · 2021
    Review
  4. Properties of Calmodulin Binding to NaNeurochemical research · 2021
    Article
  5. Structural basis of cytoplasmic NaV1.5 and NaV1.4 regulation.The Journal of general physiology · 2021
    Review
  6. [Effect of calmodulin and its mutants on binding to NaZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2020
    Article
  7. Crystal structures of CaProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Holly M IsbellDepartment of Biochemistry, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, 52242-1109, USA.ORCID 0000-0002-4055-2016
Adina M KilpatrickDepartment of Physics and Astronomy, Drake University, Des Moines, IA, 50311-4516, USA.ORCID 0000-0001-7947-4951
Zesen LinDepartment of Biochemistry, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, 52242-1109, USA.ORCID 0000-0002-1779-1967
Ryan MahlingDepartment of Biochemistry, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, 52242-1109, USA.ORCID 0000-0002-4590-2724
Madeline A SheaDepartment of Biochemistry, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, 52242-1109, USA. madeline-shea@uiowa.edu.ORCID 0000-0003-0814-7069
University of Iowa · USDrake University · US

Funding

Interdisciplinary Training Program in Pain ResearchT32NS045549 · NINDS · UNIVERSITY OF IOWA · PI KATHLEEN A SLUKA, Yuriy M Usachev · 2004 to 2026
$3.7M
MOLECULAR DISSECTION OF CALMODULIN DOMAIN INTERACTIONSR01GM057001 · NIGMS · UNIVERSITY OF IOWA · PI SHEA, MADELINE A · 1998 to 2015
$2.9M
NIGMS NIH HHS R01 GM057001NINDS NIH HHS T32 NS045549
6 · The paper itself

Abstract

Human voltage-gated sodium (Na

Indexed as

Nuclear Magnetic Resonance, BiomolecularAmino Acid MotifsAmino Acid SequenceApoproteinsCalmodulinHumansNAV1.1 Voltage-Gated Sodium ChannelNAV1.4 Voltage-Gated Sodium ChannelNAV1.7 Voltage-Gated Sodium ChannelVoltage-Gated Sodium ChannelsApoproteinsCalmodulinNAV1.1 Voltage-Gated Sodium ChannelNAV1.4 Voltage-Gated Sodium ChannelNAV1.7 Voltage-Gated Sodium ChannelSCN1A protein, humanSCN4A protein, humanSCN9A protein, humanVoltage-Gated Sodium ChannelsAllosteryCalcium signalingDomain interactionsEF-hand proteinMolecular recognitionVoltage-gated sodium channel

Identifiers

PMID29728980
PMCPMC6274588
OpenAlexW2802647311

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.