Evidence map›Paper›PMID 29728959›Full record

SynthesisJournal of cancer survivorship : research and practice2018

Systematic review of self-reported cognitive function in cancer patients following chemotherapy treatment.

Victoria J Bray, Haryana M Dhillon, Janette L Vardy

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of cancer survivorship : research and practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed, 14 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 14 syntheses or guidelines pooled it, 178 citations in OpenAlex.

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  17. Cancer-related cognitive impairment in patients with newly diagnosed aggressive lymphoma undergoing standard chemotherapy: a longitudinal feasibility study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Victoria J BrayDepartment of Medical Oncology, Liverpool Hospital, Liverpool, NSW, 2170, Australia.
Haryana M DhillonCentre for Medical Psychology & Evidence-based Decision-making, University of Sydney, Level 6, The Chris O'Brien Lifehouse, Sydney, NSW, 2006, Australia.
Janette L VardyDepartment of Medical Oncology, Concord Cancer Centre, Concord Repatriation General Hospital, Concord, NSW, 2139, Australia. janette.vardy@sydney.edu.au.
Concord Repatriation General Hospital · AULiverpool Hospital · AUUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCognitive symptoms are common in cancer patients, with up to 70% reporting cognitive symptoms following chemotherapy. These symptoms can have a major impact on how an individual functions in all aspects of their lives. This review evaluates self-reported cognitive function and its associations with neuropsychological tests and patient-reported outcomes in adult cancer patients who received chemotherapy treatment for a solid cancer.

methodsA search of multiple databases (Medline, Ovid at Nursing, PsycINFO, Allied and Complementary Medicine) from 1936 to 2017 was conducted, identifying 1563 unique articles, of which 101 met inclusion criteria.

resultsOf the 101 included studies, 48 (47%) were cross-sectional and 38 (38%) longitudinal in design, with 12 (12%) randomised controlled trials. A minority (26%) incorporated a healthy control arm in the study design, whilst the majority (79%) were in women with breast cancer. There was diversity in the assessment of self-reported cognitive symptoms. A total of 43 of 44 studies that sought an association between self-reported cognitive function and patient-reported outcomes found a moderate to strong association. Overall, 31 studies showed a lack of association between self-reported cognitive symptoms and neuropsychological results, whilst 14 studies reported a significant association between the two, but the association was often restricted to limited cognitive domains.

conclusionThe review found widespread heterogeneity in the assessment of self-reported cognitive symptoms and consistently absent or weak association with neuropsychological test scores. IMPLICATIONS FOR CANCER SURVIVORS: This research highlights the need for a standardised approach to measurement of self-reported cognitive symptoms in cancer patients.

Indexed as

Self ReportAdultAntineoplastic Combined Chemotherapy ProtocolsCancer SurvivorsCognitionCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleNeoplasmsNeuropsychological TestsRandomized Controlled Trials as TopicCancerChemotherapyCognitionCognitive symptomsSelf-reported cognitive function

Identifiers

PMID29728959
OpenAlexW2800669955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.