Evidence map›Paper›PMID 29728949›Full record

ArticleAIDS and behavior2018

Threefold Increase in PrEP Uptake Over Time with High Adherence Among Young Men Who Have Sex With Men in Chicago.

Ethan Morgan, Kevin Moran, Daniel T Ryan, Brian Mustanski, Michael E Newcomb

Abstract read
In one paragraph

Article in AIDS and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ethan MorganDepartment of Medical Social Sciences, Northwestern University, Chicago, IL, USA. ethan.morgan@northwestern.edu.ORCID http://orcid.org/0000-0001-7189-680X
Kevin MoranDepartment of Medical Social Sciences, Northwestern University, Chicago, IL, USA.
Daniel T RyanDepartment of Medical Social Sciences, Northwestern University, Chicago, IL, USA.
Brian MustanskiDepartment of Medical Social Sciences, Northwestern University, Chicago, IL, USA.
Michael E NewcombDepartment of Medical Social Sciences, Northwestern University, Chicago, IL, USA.
Northwestern University · US

Funding

The RADAR cohort study of multilevel Influences on HIV and substance useU01DA036939 · NIDA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Brian Mustanski, Michael E Newcomb · 2014 to 2026
$29.5M
Substance Use, Stress, and HIV Influences on Systemic Inflammation Among Young Men Who Have Sex With MenF32DA046313 · NIDA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MORGAN, ETHAN · 2018 to 2019
$119k
National Institute on Drug Abuse U01DA036939NIDA NIH HHS F32 DA046313NIDA NIH HHS U01 DA036939
6 · The paper itself

Abstract

The goal of this work is to better understand utilization and uptake of pre-exposure prophylaxis (PrEP) among young men who have sex with men (YMSM) and transgender women (TGW). We assessed trends and correlates of PrEP use and adherence across three time points of longitudinal data collection among 885 YMSM and TGW (aged 16-29) from the RADAR cohort in Chicago, 2015-2017. Past 6-month PrEP use increased across three visits: from 6.6 to 17.5%. In multivariable models, past 6-month PrEP use was significantly associated with participation in condomless sex, having more sexual partners, and older age. At least three-quarters of current PrEP users reported being ≥ 90% adherent to PrEP medication across all visits. Past 6-month PrEP use increased over time with those who participated in high-risk HIV behaviors also those most likely to have taken PrEP. As PrEP uptake continues to rise, more research will be needed to understand predictors of PrEP usage, as well as patterns of sexual behavior change following uptake.

Indexed as

Medication AdherencePre-Exposure ProphylaxisSexual PartnersAdolescentAdultChicagoCohort StudiesFemaleHIV InfectionsHomosexuality, MaleHumansLongitudinal StudiesMaleSafe SexSexual and Gender MinoritiesSexual BehaviorHIVLongitudinalPrEPTrendsUptake

Identifiers

PMID29728949
PMCPMC6204095
OpenAlexW2800028981

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.