Evidence map›Paper›PMID 29728942›Full record

ArticleLasers in medical science2018

Evaluation of bone repair after application of a norbixin membrane scaffold with and without laser photobiomodulation (λ 780 nm).

Adrielle Martins Monteiro Alves, Lílian Melo de Miranda Fortaleza, Antonio Luiz Martins Maia Filho, Danniel Cabral Leão Ferreira, Charllyton Luis Sena da Costa, Vicente Galber Freitas Viana, José Zilton Lima Verde Santos, Rauirys Alencar de Oliveira, Gustavo Oliveira de Meira Gusmão, Luís Eduardo Silva Soares

Abstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Evaluation of How Methacrylate Gelatin Hydrogel Loaded withJournal of functional biomaterials · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Adrielle Martins Monteiro AlvesInstituto de Pesquisa e Desenvolvimento, IP&D, Laboratório de Odontologia e Materiais Aplicados, LOMA, Universidade do Vale do Paraíba, UNIVAP, Av. Shishima Hifumi, 2911, Urbanova, São Jose dos Campos, SP, 12244-000, Brazil.
Lílian Melo de Miranda FortalezaInstituto de Pesquisa e Desenvolvimento, IP&D, Laboratório de Odontologia e Materiais Aplicados, LOMA, Universidade do Vale do Paraíba, UNIVAP, Av. Shishima Hifumi, 2911, Urbanova, São Jose dos Campos, SP, 12244-000, Brazil.
Antonio Luiz Martins Maia FilhoNúcleo de Pesquisa em Biotecnologia e Biodiversidade, Universidade Estadual do Piauí, Teresina, PI, Brazil.
Danniel Cabral Leão FerreiraNúcleo de Pesquisa em Biotecnologia e Biodiversidade, Universidade Estadual do Piauí, Teresina, PI, Brazil.
Charllyton Luis Sena da CostaCurso de Farmácia da Faculdade Santo Agostinho, Teresina, PI, Brazil.
Vicente Galber Freitas VianaInstituto Federal do Piauí, Teresina, PI, Brazil.
José Zilton Lima Verde SantosUniversidade Estadual do Piauí, Teresina, PI, Brazil.
Rauirys Alencar de OliveiraCurso de Fisioterapia, Centro Universitário UNINOVAFAPI, Teresina, PI, Brazil.
Gustavo Oliveira de Meira GusmãoDepartamento de Física, Universidade Federal do Piauí, Teresina, PI, Brazil.
Luís Eduardo Silva SoaresInstituto de Pesquisa e Desenvolvimento, IP&D, Laboratório de Odontologia e Materiais Aplicados, LOMA, Universidade do Vale do Paraíba, UNIVAP, Av. Shishima Hifumi, 2911, Urbanova, São Jose dos Campos, SP, 12244-000, Brazil. lesoares@univap.br.
Universidade do Vale do Paraíba · BRUniversidade Estadual do Piau · BRCentro Universitário UNINOVAFAPI · BRInstituto Federal do Piauí · BRUniversidade Federal do Piauí · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biocompatible membranes are widely used in medicine to stimulate bone repair. Several studies have demonstrated that laser photobiomodulation (PBM) also stimulates osteoblast proliferation and osteogenesis at the fracture site, leading to a greater deposition of bone mass and accelerating the process of bone consolidation. This work assessed the therapeutic effect of 780-nm laser PBM and a polystyrene membrane coated with norbixin and collagen (PSNC) on bone healing in rats with calvarial bone defect. Histological staining, Raman spectroscopy, and scanning electron microscopy (SEM) were used to evaluate the bone repair process. Four experimental treatment groups were compared: C, control; M, membrane only; L, laser PBM only; and ML, membrane + laser PBM. A bone defect was created in the calvaria of each animal, with each group subdivided into two subgroups that underwent euthanasia after 15 and 30 days treatment. The L and ML groups were irradiated (λ = 780 nm, ED = 6 J/cm

Indexed as

AnimalsBone and BonesCarotenoidsCollagenDurapatiteLow-Level Light TherapyMaleMicroscopy, Electron, ScanningPolystyrenesRats, WistarSkullSpectrum Analysis, RamanWound HealingCarotenoidsCollagenDurapatitenorbixinPolystyrenesBiocompatible membraneBone histologyBone repairLaser photobiomodulationRaman spectroscopyScanning electron microscopy (SEM)

Identifiers

PMID29728942
OpenAlexW2800835002

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.