ArticleEuropean journal of pediatrics2018
Evaluation of the current use of imaging modalities and pathogen detection in children with acute osteomyelitis and septic arthritis.
Article in European journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03827980 (LOOP- Long- and Midterm Outcomes of Osteoarticular Infections in Paediatric Patients.), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
LOOP- Long- and Midterm Outcomes of Osteoarticular Infections in Paediatric Patients.
Who cites it
15 citing papers in PubMed, 51 citations in OpenAlex.
- Hip Joint Synovial Cavity Thickness in Early Juvenile Idiopathic Arthritis Without Effusion: A Cross-Sectional Ultrasound Study.Journal of clinical medicine · 2026Article
- Development of a multicentre cohort study to understand the role of MRI and ultrasound in the diagnosis of acute haematogenous bone and joint infection in children (the PIC Bone study) : a study protocol.Bone & joint open · 2025Article
- [Arthritis and osteomyelitis in childhood and adolescence-Bacterial and nonbacterial].Zeitschrift fur Rheumatologie · 2025Review
- Osteomyelitis and Septic Arthritis of the Upper Extremity in Pediatric Patients.Current reviews in musculoskeletal medicine · 2025Review
- Review
- Microbiological Spectrum of Osteoarticular Infections and Their Management in Mongolian Children.Global pediatric health · 2024Article
- A transformer-based deep learning model for identifying the occurrence of acute hematogenous osteomyelitis and predicting blood culture results.Frontiers in microbiology · 2024Article
- Radiometal chelators for infection diagnostics.Frontiers in nuclear medicine · 2023Article
- Developments in diagnosis and treatment of paediatric septic arthritis.World journal of orthopedics · 2022Review
- Measuring complications of serious pediatric emergencies using ICD-10.Health services research · 2021Article
- Pediatric Septic Arthritis of the Knee Due to a Multi-SensitiveChildren (Basel, Switzerland) · 2021Article
- A Comparison of the Epidemiology, Clinical Features, and Treatment of Acute Osteomyelitis in Hospitalized Children in Latvia and Norway.Medicina (Kaunas, Lithuania) · 2021Article
- Long-Term Outcomes of Acute Osteoarticular Infections in Children.Frontiers in pediatrics · 2020Article
- Pyogenic sacroiliitis in children: don't forget the very young.European journal of pediatrics · 2019Article
- Role of Magnetic Resonance Imaging in Concomitant Periarticular Infections in Septic Arthritis of Large Joints in Children: A Systematic Review.Journal of the West African College of SurgeonsArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diagnostic tools for the management of acute osteomyelitis (OM) and septic arthritis (SA) have improved over the last decade. To investigate the influence and availability of magnetic resonance imaging (MRI) and nucleic acid testing (NAT), a retrospective cohort study was done. Patients admitted with acute OM or SA between 2005 and 2014 were identified using ICD-10 discharge codes. Ninety-six children were identified: OM, n = 45; SA, n = 42; and OM + SA, n = 9. Diagnostic imaging was performed in 100% of OM or OM + SA and 95% of SA patients. MRI was performed in 85% of OM patients, 26% of SA patients and 100% OM + SA patients. In patients with OM or SA, concomitant joint/bone involvement was detected in 24 and 36% of patients, respectively. In 58% of patients, a pathogen was detected (Staphylococcus aureus, Streptococcus pyogenes and Streptococcus pneumoniae being most common). Blood and tissue culture were positive in 41 and 86% for OM patients and in 14 and 41%, respectively, for SA patients. In 42% of patients, no pathogen was identified, of which 40% had no material for blood or tissue culture/NAT taken.
conclusionOptimal use of imaging modalities including MRI and systematic pathogen detection including NAT should be advocated to limit use of broad spectrum antibiotics and treatment duration. What is Known: • Magnetic resonance imaging and sonography have the best sensitivity for detection of acute osteomyelitis and septic arthritis in children. • Systematic use of blood cultures, tissue cultures and nucleic acid testing improves pathogen detection in children with acute osteomyelitis and septic arthritis. What is New: • The added value of imaging modalities other than magnetic resonance and sonography for detection of osteomyelitis and septic arthritis is limited, and their routine use should be questioned. • Despite availability of optimal pathogen detection methods, missed opportunities to improve pathogen detection are frequent.
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