ArticleScientific reports2018
Applications and efficiencies of the first cat 63K DNA array.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- First genome-wide association study investigating blood pressure and renal traits in domestic cats.Scientific reports · 2022Pooled it
- Widespread genetic testing controls inherited polycystic kidney disease while avoiding inbreeding in cats.BMC genomics · 2026Article
- Transcriptomes of thirteen healthy feline tissue types.BMC genomics · 2025Article
- Chromosome-scale assembly with improved annotation provides insights into breed-wide genomic structure and diversity in domestic cats.Journal of advanced research · 2025Article
- Shared alleles and genetic structures in different Thai domestic cat breeds: the possible influence of common racial origins.Genomics & informatics · 2024Article
- Different Founding Effects Underlie Dominant Blue Eyes (DBE) in the Domestic Cat.Animals : an open access journal from MDPI · 2024Article
- Selection Signatures Reveal Candidate Genes for the Cornish Rex Breed-Specific Phenotype.Genes · 2024Article
- Article
- Tracking footprints of artificial and natural selection signatures in breeding and non-breeding cats.Scientific reports · 2022Article
- Feline Fertility: Consequences of inbreeding and implications for reproductive fitness.Journal of feline medicine and surgery · 2022Review
- Reproductive Management in Catteries: Optimising health and wellbeing through veterinarian-breeder collaboration.Journal of feline medicine and surgery · 2022Review
- Genetic Aspects of Corneal Sequestra in a Population of Persian, Himalayan and Exotic Cats.Animals : an open access journal from MDPI · 2022Article
- Genetic epidemiology of blood type, disease and trait variants, and genome-wide genetic diversity in over 11,000 domestic cats.PLoS genetics · 2022Article
- An ancient haplotype containing antimicrobial peptide gene variants is associated with severe fungal skin disease in Persian cats.PLoS genetics · 2022Article
- Complex Feline Disease Mapping Using a Dense Genotyping Array.Frontiers in veterinary science · 2022Article
- More Than a Moggy; A Population Genetics Analysis of the United Kingdom's Non-Pedigree Cats.Genes · 2021Article
- Standardization of a SNP panel for parentage verification and identification in the domestic cat (Felis silvestris catus).Animal genetics · 2021Article
- Development and validation of a 1 K sika deer (Cervus nippon) SNP Chip.BMC genomic data · 2021Article
- Exploiting genomic synteny in Felidae: cross-species genome alignments and SNV discovery can aid conservation management.BMC genomics · 2021Article
- Reliability and Validity of Seven Feline Behavior and Personality Traits.Animals : an open access journal from MDPI · 2021Article
Corrections and comments
- Erratum issued
- Erratum issued
Authors and funding
32 authors.
Funding
Abstract
The development of high throughput SNP genotyping technologies has improved the genetic dissection of simple and complex traits in many species including cats. The properties of feline 62,897 SNPs Illumina Infinium iSelect DNA array are described using a dataset of over 2,000 feline samples, the most extensive to date, representing 41 cat breeds, a random bred population, and four wild felid species. Accuracy and efficiency of the array's genotypes and its utility in performing population-based analyses were evaluated. Average marker distance across the array was 37,741 Kb, and across the dataset, only 1% (625) of the markers exhibited poor genotyping and only 0.35% (221) showed Mendelian errors. Marker polymorphism varied across cat breeds and the average minor allele frequency (MAF) of all markers across domestic cats was 0.21. Population structure analysis confirmed a Western to Eastern structural continuum of cat breeds. Genome-wide linkage disequilibrium ranged from 50-1,500 Kb for domestic cats and 750 Kb for European wildcats (Felis silvestris silvestris). Array use in trait association mapping was investigated under different modes of inheritance, selection and population sizes. The efficient array design and cat genotype dataset continues to advance the understanding of cat breeds and will support monogenic health studies across feline breeds and populations.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.