Evidence map›Paper›PMID 29728628›Full record

ArticleScientific reports2018

Chronic features of allergic asthma are enhanced in the absence of resistin-like molecule-beta.

Kim S LeMessurier, Maneesha Palipane, Meenakshi Tiwary, Brian Gavin, Amali E Samarasinghe

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Regulatory Peptides in Asthma.International journal of molecular sciences · 2021
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Kim S LeMessurierDepartment of Paediatrics, University of Tennessee Health Science Center, Memphis, TN, 38103, USA.
Maneesha PalipaneDepartment of Paediatrics, University of Tennessee Health Science Center, Memphis, TN, 38103, USA.
Meenakshi TiwaryDepartment of Paediatrics, University of Tennessee Health Science Center, Memphis, TN, 38103, USA.
Brian GavinDepartment of Paediatrics, University of Tennessee Health Science Center, Memphis, TN, 38103, USA.
Amali E SamarasingheDepartment of Paediatrics, University of Tennessee Health Science Center, Memphis, TN, 38103, USA. asamaras@uthsc.edu.ORCID 0000-0002-3104-2823
University of Tennessee Health Science Center · US

Funding

Eosinophils as Regulators of Host Immunity against Influenza InfectionsR01AI125481 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI SAMARASINGHE, AMALI · 2017 to 2021
$1.9M
NIAID NIH HHS R01 AI125481
6 · The paper itself

Abstract

Asthma is characterized by inflammation and architectural changes in the lungs. A number of immune cells and mediators are recognized as initiators of asthma, although therapeutics based on these are not always effective. The multifaceted nature of this syndrome necessitate continued exploration of immunomodulators that may play a role in pathogenesis. We investigated the role of resistin-like molecule-beta (RELM-β), a gut antibacterial, in the development and pathogenesis of Aspergillus-induced allergic airways disease. Age and gender matched C57BL/6J and Retnlb

Indexed as

Disease SusceptibilityAirway RemodelingAllergensAnimalsAsthmaBiomarkersCytokinesDisease Models, AnimalGoblet CellsHormones, EctopicImmunity, HumoralImmunoglobulin AInflammation MediatorsIntercellular Signaling Peptides and ProteinsLungMetaplasiaAllergensBiomarkersCytokinesHormones, EctopicImmunoglobulin AInflammation MediatorsIntercellular Signaling Peptides and ProteinsRetnlb protein, mouse

Identifiers

PMID29728628
PMCPMC5935686
OpenAlexW2800996185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.