Evidence map›Paper›PMID 29728510›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Rapid Turnover and High Production Rate of Myeloid Cells in Adult Rhesus Macaques with Compensations during Aging.

Ziyuan He, Carolina Allers, Chie Sugimoto, Nursarat Ahmed, Hideki Fujioka, Woong-Ki Kim, Elizabeth S Didier, Marcelo J Kuroda

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Article
  3. Neutrophil kinetics ofFrontiers in cellular and infection microbiology · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ziyuan HeDivision of Immunology, Tulane National Primate Research Center, Tulane University Health Science Center, Covington, LA 70433.ORCID 0000-0003-3556-8248
Carolina AllersDivision of Immunology, Tulane National Primate Research Center, Tulane University Health Science Center, Covington, LA 70433.ORCID 0000-0001-8576-770X
Chie SugimotoDivision of Immunology, Tulane National Primate Research Center, Tulane University Health Science Center, Covington, LA 70433.
Nursarat AhmedDivision of Immunology, Tulane National Primate Research Center, Tulane University Health Science Center, Covington, LA 70433.
Hideki FujiokaCenter for Computational Science, Tulane University, New Orleans, LA 70118.
Woong-Ki KimDepartment of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA 23507; and.
Elizabeth S DidierDivision of Microbiology, Tulane National Primate Research Center, Tulane University Health Science Center, Covington, LA 70433.ORCID 0000-0002-8343-7202
Marcelo J KurodaDivision of Immunology, Tulane National Primate Research Center, Tulane University Health Science Center, Covington, LA 70433; mjkuroda@ucdavis.edu.
Tulane University · USEastern Virginia Medical School · US

Funding

National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
Macrophages in the pathogenesis of AIDSR01AI097059 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI KURODA, MARCELO J · 2012 to 2016
$4.0M
Targeting Brain Macrophage Reservoirs of SIV during HAARTR01MH107333 · NIMH · EASTERN VIRGINIA MEDICAL SCHOOL · PI KIM, WOONG-KI · 2015 to 2019
$3.4M
Targeting Macrophages in Aging SIV-Infected Rhesus MacaquesR01HL139278 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DIDIER, ELIZABETH SCHMIDT, KURODA, MARCELO J · 2017 to 2020
$2.9M
Targeting HIV Lung Reservoir in the Macaque ModelR33AI110163 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KURODA, MARCELO J · 2016 to 2018
$1.5M
Effects of Opioids on SIV Reservoirs in Brain Macrophages of Rhesus MacaquesR21DA041017 · NIDA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KURODA, MARCELO J · 2015 to 2017
$1.1M
Rhesus Macaque Model of Accelerated AgingR56AG052349 · NIA · TULANE UNIVERSITY OF LOUISIANA · PI DIDIER, ELIZABETH SCHMIDT · 2016 to 2016
$845k
Targeting HIV Lung Reservoir in the Macaque ModelR21AI110163 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI KURODA, MARCELO J · 2014 to 2015
$457k
Targeting Brain Macrophage Reservoirs of Infection in Pediatric NeuroAIDSR21MH108458 · NIMH · EASTERN VIRGINIA MEDICAL SCHOOL · PI KIM, WOONG-KI · 2015 to 2016
$442k
NHLBI NIH HHS R01 HL139278NIAID NIH HHS R01 AI097059NIAID NIH HHS R21 AI110163NIAID NIH HHS R33 AI110163NIA NIH HHS R56 AG052349NIDA NIH HHS R21 DA041017NIH HHS P51 OD011104NIH HHS P51 OD011107NIMH NIH HHS R01 MH107333NIMH NIH HHS R21 MH108458
6 · The paper itself

Abstract

Neutrophils, basophils, and monocytes are continuously produced in bone marrow via myelopoiesis, circulate in blood, and are eventually removed from circulation to maintain homeostasis. To quantitate the kinetics of myeloid cell movement during homeostasis, we applied 5-bromo-2'-deoxyuridine pulse labeling in healthy rhesus macaques (

Indexed as

AgingAnimalsBasophilsBone Marrow CellsEosinophilsHalf-LifeHomeostasisMacaca mulattaMaleMonocytesMyeloid CellsNeutrophils

Identifiers

PMID29728510
PMCPMC6263173
OpenAlexW2801660454

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.