Evidence map›Paper›PMID 29728423›Full record

ArticleThe Journal of cell biology2018

Autoinhibition of kinesin-1 is essential to the dendrite-specific localization of Golgi outposts.

Michael T Kelliher, Yang Yue, Ashley Ng, Daichi Kamiyama, Bo Huang, Kristen J Verhey, Jill Wildonger

Abstract read
In one paragraph

Article in The Journal of cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. The Neuronal Golgi Network and Its Acolytes.Sub-cellular biochemistry · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Live Imaging of Golgi Outposts in Drosophila Dendritic Arbors.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael T KelliherIntegrated Program in Biochemistry, University of Wisconsin-Madison, Madison, WI.ORCID 0000-0001-5388-1217
Yang YueDepartment of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI.ORCID 0000-0002-8302-9778
Ashley NgBiochemistry Department, University of Wisconsin-Madison, Madison, WI.
Daichi KamiyamaDepartment of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA.
Bo HuangDepartment of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA.ORCID 0000-0003-1704-4141
Kristen J VerheyDepartment of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI.ORCID 0000-0001-9329-4981
Jill WildongerBiochemistry Department, University of Wisconsin-Madison, Madison, WI wildonger@wisc.edu.ORCID 0000-0002-6462-5830

Funding

Regulation of the molecular motor kinesin-IR01GM070862 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VERHEY, KRISTEN J. · 2005 to 2018
$4.2M
MOLECULAR MOTORS AND NEURONAL MICROTUBULE POLARITYR01NS102385 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI WILDONGER, JILL C · 2017 to 2022
$1.6M
Multimerized GFP probe for live cell imagingR21EB022798 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUANG, BO · 2016 to 2017
$436k
The Role of Dscam Dock and Cdc42 Effectors in Prosophilia Neuron DendritogenesisR21MH101688 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUANG, BO, KAMIYAMA, DAICHI · 2014 to 2015
$434k
NIBIB NIH HHS R21 EB022798NIGMS NIH HHS R01 GM070862NIMH NIH HHS R21 MH101688NINDS NIH HHS R01 NS102385
6 · The paper itself

Abstract

Neuronal polarity relies on the selective localization of cargo to axons or dendrites. The molecular motor kinesin-1 moves cargo into axons but is also active in dendrites. This raises the question of how kinesin-1 activity is regulated to maintain the compartment-specific localization of cargo. Our in vivo structure-function analysis of endogenous

Indexed as

AnimalsAxonsCell PolarityCells, CulturedDendritesDrosophila melanogasterDrosophila ProteinsGolgi ApparatusKinesinsMicrotubulesMutationNeuronsProtein TransportDrosophila ProteinsKhc protein, DrosophilaKinesins

Identifiers

PMID29728423
PMCPMC6028532

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.