Evidence map›Paper›PMID 29728364›Full record

ArticleDiabetes care2018

Gestational Diabetes Mellitus and Renal Function: A Prospective Study With 9- to 16-Year Follow-up After Pregnancy.

Shristi Rawal, Sjurdur F Olsen, Louise G Grunnet, Ronald C Ma, Stefanie N Hinkle, Charlotta Granström, Jing Wu, Edwina Yeung, James L Mills, Yeyi Zhu and 7 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05952739 (Maternal Endocrine System and Metabolic Diseases and Offspring Health), which is not on this map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05952739 unknown statusnot on this mapstarted 2023, after this paper: background citation

Maternal Endocrine System and Metabolic Diseases and Offspring Health: Prediction Within a Birth Cohort

TypeobservationalSponsorPeking Union Medical College HospitalRan2023 to 2025Enrolled300ConditionsThyroid Dysfunction, Diabetes Mellitus
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Kidney Dysfunction Following Gestational Diabetes Mellitus.Clinical journal of the American Society of Nephrology : CJASN · 2025
    Article
  12. Article
  13. Diabetes and women's health.Journal of diabetes investigation · 2025
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Promoting Healthy Longevity Should Start Young: A Life Course Journey.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 10 institutions in 4 countries.

Shristi RawalEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD.
Sjurdur F OlsenCentre for Fetal Programming, Statens Serum Institut, Copenhagen, Denmark.
Louise G GrunnetDepartment of Endocrinology, Rigshospitalet University Hospital, Copenhagen, Denmark.ORCID 0000-0003-2298-2597
Ronald C MaDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0002-1227-803X
Stefanie N HinkleEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD.
Charlotta GranströmCentre for Fetal Programming, Statens Serum Institut, Copenhagen, Denmark.
Jing WuEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD.
Edwina YeungEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD.
James L MillsEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD.
Yeyi ZhuDivision of Research, Kaiser Permanente Northern California, Oakland, CA.ORCID 0000-0002-7296-738X
Wei BaoDepartment of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA.ORCID 0000-0002-7301-5786
Sylvia H LeyDepartment of Nutrition, Harvard T.H. Chan School of Public Health, and Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Frank B HuDepartment of Nutrition, Harvard T.H. Chan School of Public Health, and Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Peter DammCenter for Pregnant Women with Diabetes, Department of Obstetrics, Rigshospitalet, and Institute of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Allan VaagDepartment of Endocrinology, Rigshospitalet University Hospital, Copenhagen, Denmark.
Michael Y TsaiDepartment of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN.
Cuilin ZhangEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD zhangcu@mail.nih.gov.ORCID 0000-0002-8014-2708
National Institutes of Health · USBrigham and Women's Hospital · USRigshospitalet · DKStatens Serum Institut · DKChinese University of Hong Kong · HKKaiser Permanente · USRutgers, The State University of New Jersey · USUniversity of Copenhagen · DKUniversity of Iowa · USUniversity of Minnesota · US

Funding

Diabetes & Women's Health Study: long term health implications of GDMZIAHD008916 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI YEUNG, EDWINA · 2011 to 2022
$3.3M
NICHD NIH HHS HHSN275201000020CNICHD NIH HHS HHSN275201100002CNICHD NIH HHS HHSN275201100002GNICHD NIH HHS HHSN275201300026INICHD NIH HHS HHSN275201500003C
6 · The paper itself

Abstract

objectiveTo examine whether gestational diabetes mellitus (GDM), independent of subsequent diabetes, is an early risk factor for renal impairment long term after the index pregnancy. RESEARCH DESIGN AND

methodsIn the Diabetes & Women's Health (DWH) study (2012-2016), we examined the independent and joint associations of GDM and subsequent diabetes with long-term renal function among 607 women with and 619 women without GDM in the Danish National Birth Cohort (DNBC) index pregnancy (1996-2002). At median follow-up of 13 years after the index pregnancy, serum creatinine (mg/dL) and urinary albumin (mg/L) and creatinine (mg/dL) were measured, from which estimated glomerular filtration rate (eGFR) (mL/min/1.73 m

resultsCompared with women without GDM or subsequent diabetes, women with a GDM history had significantly higher eGFR even if they had not subsequently developed diabetes (adjusted β-coefficient [95% CI] = 3.3 [1.7, 5.0]). Women who had a GDM history and later developed diabetes (

conclusionsWomen who develop GDM in pregnancy were more likely to show increased eGFR levels 9-16 years postpartum, which could indicate early stages of glomerular hyperfiltration and renal damage. However, only those who subsequently developed diabetes showed overt renal damage as evidenced by elevated UACR.

Indexed as

AdultCreatinineDenmarkDiabetes, GestationalFemaleFollow-Up StudiesGlomerular Filtration RateHumansHypertensionKidneyKidney DiseasesKidney Function TestsLongitudinal StudiesPostpartum PeriodPregnancyRenal Insufficiency, ChronicCreatinine

Identifiers

PMID29728364
PMCPMC6014536
OpenAlexW2799535074

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.