Evidence map›Paper›PMID 29728177›Full record

ArticleInternational journal of pediatric otorhinolaryngology2018

Modeling congenital nasal pyriform aperture stenosis using computational fluid dynamics.

Tirth R Patel, Chengyu Li, Jillian Krebs, Kai Zhao, Prashant Malhotra

Abstract readCase Reports
In one paragraph

Article in International journal of pediatric otorhinolaryngology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Pyriform Aperture Enlargement Through a Rhinoplasty Approach.Aesthetic surgery journal. Open forum · 2024
    Article
  3. Article
  4. Computational fluid dynamics modelling of human upper airway: A review.Computer methods and programs in biomedicine · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tirth R PatelCollege of Medicine, The Ohio State University, 370 West 9th Avenue, Columbus, OH 43210, USA. Electronic address: tirth.patel@osumc.edu.
Chengyu LiDepartment of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, 915 Olentangy River Road Suite 4000, Columbus, OH 43212, USA. Electronic address: chengyu.li@osumc.edu.
Jillian KrebsDepartment of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, 915 Olentangy River Road Suite 4000, Columbus, OH 43212, USA.
Kai ZhaoDepartment of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, 915 Olentangy River Road Suite 4000, Columbus, OH 43212, USA. Electronic address: kai.zhao@osumc.edu.
Prashant MalhotraDepartment of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, 915 Olentangy River Road Suite 4000, Columbus, OH 43212, USA; Department of Otolaryngology, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA. Electronic address: prashant.malhotra@nationwidechildrens.org.

Funding

Objective evaluation of conductive olfactory losses & nasal obstruction symptomsR01DC013626 · NIDCD · OHIO STATE UNIVERSITY · PI ZHAO, KAI · 2015 to 2018
$1.6M
NIDCD NIH HHS R01 DC013626
6 · The paper itself

Abstract

objectivesCongenital nasal pyriform aperture stenosis (CNPAS) is a rare cause of airway obstruction in the neonate. Computational airway modeling has not been done in neonates and young infants to understand the impact of stenosis on functional nasal airflow. In this study, we 1) applied computational fluid dynamics (CFD) model to the airway of a neonate with CNPAS and 2) compare airflow dynamics of a normal and CNPAS airway.

methodsThree-dimensional models of the nasal airway of a normal neonate and a neonate with CNPAS were created using computed tomography scans of the facial bones. Measured anatomic parameters included volume, surface area, and cross-sectional area. CFD simulation was then performed. Simulated flow parameters included pressure, average velocity, and resistance.

resultsThe neonate with CNPAS had a lesser volume (2.74 cm

conclusionsCFD analysis can be performed on airways of neonates with nasal obstruction, such as in CNPAS. A CFD model may help characterize severity of airway obstruction as it can predict the three-dimensional pattern of airflow. Determining the role of CFD in clinical management of CNPAS requires further investigation.

Indexed as

Computer SimulationConstriction, PathologicFacial BonesFemaleHumansHydrodynamicsImaging, Three-DimensionalInfantInfant, NewbornMaleNasal CavityNasal ObstructionTomography, X-Ray ComputedAirway modelingCongenital pyriform aperture stenosisFluid dynamicsPediatric airway

Identifiers

PMID29728177
PMCPMC5942217

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.