Evidence map›Paper›PMID 29727615›Full record

ArticleMolecular cell2018

To Claim Growth Turf, mTOR Says SOD Off.

Hyewon Kong, Navdeep S Chandel

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Molecular cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Everolimus alleviates CD4GeroScience · 2024
    Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hyewon KongDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Navdeep S ChandelDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. Electronic address: nav@northwestern.edu.
Northwestern University · US

Funding

CARCINOGENESIS TRAINING PROGRAMT32CA009560 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Kathleen Janee Green · 1986 to 2026
$8.4M
NCI NIH HHS T32 CA009560
6 · The paper itself

Abstract

Maintaining redox balance in cancer cells is essential for tumor development and progression. In this issue of Molecular Cell, Tsang et al. (2018) identify an evolutionarily conserved mTORC1-dependent mechanism by which cancer cells control redox homeostasis in ischemic tumor microenvironment.

Indexed as

Mechanistic Target of Rapamycin Complex 1NutrientsOxidation-ReductionPhosphorylationSignal TransductionSuperoxide Dismutase-1TOR Serine-Threonine KinasesMechanistic Target of Rapamycin Complex 1NutrientsSuperoxide Dismutase-1TOR Serine-Threonine Kinases

Identifiers

PMID29727615
OpenAlexW2799385659

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.