Evidence map›Paper›PMID 29727159›Full record

ReviewACS nano2018

Nongenetic Optical Methods for Measuring and Modulating Neuronal Response.

John F Zimmerman, Bozhi Tian

Abstract readReview
In one paragraph

Review in ACS nano, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Optoelectronic Neural Interfaces Based on Quantum Dots.ACS applied materials & interfaces · 2022
    Review
  12. Chemical reviews · 2022
    Review
  13. Article
  14. TiACS nano · 2021
    Article
  15. Article
  16. Article
  17. Review
  18. Plasmon-Coupled Photocapacitor Neuromodulators.ACS applied materials & interfaces · 2020
    Article
  19. Membrane Environment Enables Ultrafast Isomerization of Amphiphilic Azobenzene.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

John F ZimmermanJohn A. Paulson School of Engineering and Applied Sciences , Harvard University , Cambridge , Massachusetts 02138 , United States.
Bozhi TianDepartment of Chemistry, the James Franck Institute, the Institute for Biophysical Dynamics , University of Chicago , Chicago , Illinois 60637 , United States.ORCID 0000-0003-0593-0023

Funding

Organ Design and Engineering Training Program (ODET Program)T32EB016652 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI BONVENTRE, JOSEPH VINCENT · 2014 to 2023
$3.5M
Silicon-based Injectable Micro-gels for Non-genetic and Wireless Modulation of Neurons, Cardiomyocytes and Neuromuscular SystemDP2NS101488 · NINDS · UNIVERSITY OF CHICAGO · PI TIAN, BOZHI · 2016 to 2016
$2.4M
NIBIB NIH HHS T32 EB016652NINDS NIH HHS DP2 NS101488
6 · The paper itself

Abstract

The ability to probe and modulate electrical signals sensitively at cellular length scales is a key challenge in the field of electrophysiology. Electrical signals play integral roles in regulating cellular behavior and in controlling biological function. From cardiac arrhythmias to neurodegenerative disorders, maladaptive phenotypes in electrophysiology can result in serious and potentially deadly medical conditions. Understanding how to monitor and to control these behaviors precisely and noninvasively represents an important step in developing next-generation therapeutic devices. As we develop a deeper understanding of neural network formation, electrophysiology has the potential to offer fundamental insights into the inner working of the brain. In this Perspective, we explore traditional methods for examining neural function, discuss recent genetic advances in electrophysiology, and then focus on the latest innovations in optical sensing and stimulation of action potentials in neurons. We emphasize nongenetic optical methods, as these provide high spatiotemporal resolution and can be achieved with minimal invasiveness.

Indexed as

Optical DevicesAnimalsElectrochemical TechniquesHumansNanowiresNeuronsPhotochemical ProcessesSiliconSilicon

Identifiers

PMID29727159
PMCPMC6161493

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.