Evidence map›Paper›PMID 29726906›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2019

Sedentary Behavior and Prevalent Diabetes in 6,166 Older Women: The Objective Physical Activity and Cardiovascular Health Study.

John Bellettiere, Genevieve N Healy, Michael J LaMonte, Jacqueline Kerr, Kelly R Evenson, Eileen Rillamas-Sun, Chongzhi Di, David M Buchner, Melbourne F Hovell, Andrea Z LaCroix

Abstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  5. Observational
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  7. Article
  8. Linking Pathogenesis to Fall Risk in Multiple Sclerosis.Archives of internal medicine research · 2025
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  13. Exercise and vascular function in sedentary lifestyles in humans.Pflugers Archiv : European journal of physiology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

John BellettiereDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla.
Genevieve N HealyThe University of Queensland, School of Public Health, Australia.
Michael J LaMonteDepartment of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo SUNY.
Jacqueline KerrDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla.
Kelly R EvensonDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina Chapel Hill, Seattle, WA.
Eileen Rillamas-SunDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA.
Chongzhi DiDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA.
David M BuchnerUniversity of Illinois at Urbana-Champaign.
Melbourne F HovellCenter for Behavioral Epidemiology and Community Health (C-BEACH), Graduate School of Public Health, San Diego State University, California.
Andrea Z LaCroixDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla.

Funding

UCSD Integrated Cardiovascular Epidemiology FellowshipT32HL079891 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Matthew A Allison · 2007 to 2026
$6.7M
Objective Physical Activity and Cardiovascular Health in Women Aged 80 and OlderR01HL105065 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI LACROIX, ANDREA Z. · 2011 to 2014
$5.0M
Statistical methods for analyzing objectively measured physical activity dataR01HL130483 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Chongzhi Di · 2016 to 2026
$4.4M
UC San Diego Clinical and Translational Research InstituteTL1TR001443 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEPP, COLIN A. · 2015 to 2019
$3.4M
NCATS NIH HHS TL1 TR001443NHLBI NIH HHS HHSN268201600001CNHLBI NIH HHS HHSN268201600002CNHLBI NIH HHS HHSN268201600003CNHLBI NIH HHS HHSN268201600004CNHLBI NIH HHS HHSN268201600018CNHLBI NIH HHS R01 HL105065NHLBI NIH HHS R01 HL130483NHLBI NIH HHS T32 HL079891
6 · The paper itself

Abstract

backgroundWe examined associations of sedentary time and sedentary accumulation patterns (ie, how sedentary time is accumulated) with prevalent diabetes in an ethnically diverse cohort of older women.

methodsCommunity-dwelling women aged 63-99 (n = 6,116; median age = 79) wore ActiGraph GT3X+ accelerometers 24 h/day for up to 7 days from which we derived average daily sedentary time and three measures of sedentary accumulation patterns: breaks in sedentary time, usual sedentary bout duration, and alpha. Odds ratios (ORs) and 95% confidence intervals (CIs) for prevalent diabetes were estimated using multivariable logistic regression.

resultsTwenty-one percent (n = 1,282) of participants had diabetes. Women in the highest quartile of sedentary time (≥10.3 h/day) had higher odds of diabetes (OR = 2.18; 95% CI = 1.77-2.70) than women in the lowest quartile (≤8.3 h/day). Prolonged accumulation patterns (ie, accumulating sedentary time in longer sedentary bouts) was associated with higher odds of diabetes than regularly interrupted patterns (comparing quartiles with the most vs least prolonged patterns: usual bout duration OR = 1.57, 95% CI = 1.28-1.92; alpha OR = 1.61, 95% CI = 1.32-1.97); however, there was no significant association for breaks in sedentary time (OR = 1.00, 95% CI = 0.82-1.20).

conclusionsHigh levels of sedentary time and accumulating it in prolonged patterns were associated with increased odds of diabetes among older women.

Indexed as

ExerciseSedentary BehaviorAccelerometryAgedAged, 80 and overCohort StudiesDiabetes MellitusFemaleHumansLogistic ModelsMiddle AgedOdds RatioPrevalenceRisk FactorsTime FactorsDiabetes preventionSedentary accumulation patternsSedentary behaviorSedentary behavior patternsType 2 diabetes

Identifiers

PMID29726906
PMCPMC6376101

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.