Evidence map›Paper›PMID 29726021›Full record

ArticleClinical cardiology2018

Etiologies, predictors, and economic impact of readmission within 1 month among patients with takotsubo cardiomyopathy.

Mahek Shah, Pradhum Ram, Kevin Bryan U Lo, Natee Sirinvaravong, Brijesh Patel, Byomesh Tripathi, Shantanu Patil, Vincent M Figueredo

Abstract readMulticenter Study
In one paragraph

Article in Clinical cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  7. "Obesity paradox" and takotsubo syndrome.International journal of cardiology. Cardiovascular risk and prevention · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mahek ShahDepartment of Cardiology, Lehigh Valley Hospital, Allentown, Pennsylvania.ORCID http://orcid.org/0000-0002-5065-3355
Pradhum RamDepartment of Medicine, Albert Einstein Medical Center, Philadelphia, Pennsylvania.ORCID http://orcid.org/0000-0003-3406-9260
Kevin Bryan U LoDepartment of Medicine, Albert Einstein Medical Center, Philadelphia, Pennsylvania.ORCID http://orcid.org/0000-0001-7088-6677
Natee SirinvaravongDepartment of Medicine, Albert Einstein Medical Center, Philadelphia, Pennsylvania.
Brijesh PatelDepartment of Cardiology, Lehigh Valley Hospital, Allentown, Pennsylvania.ORCID http://orcid.org/0000-0001-8973-8228
Byomesh TripathiDepartment of Internal Medicine, St. Luke's Roosevelt Hospital Center, New York, New York.
Shantanu PatilDepartment of Medicine, SSM Health St. Mary's Hospital, St. Louis, Missouri.
Vincent M FigueredoDepartment of Cardiology, Albert Einstein Medical Center, Philadelphia, Pennsylvania.ORCID http://orcid.org/0000-0003-0301-5649

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLimited data exist on readmission among patients with takotsubo cardiomyopathy (TC), a commonly reversible cause of heart failure. HYPOTHESIS: We sought to identify etiologies and predictors for readmission among TC patients.

methodsWe queried the National Readmissions Database for 2013-2014 to identify patients with primary admission for TC using ICD-9-CM code 429.83. Patients readmitted to hospital within 1 month after discharge were further evaluated to identify etiologies, predictors, and resultant economic burden of readmission. Additionally, we analyzed readmission for TC at 6 months.

resultsWe studied 5997 patients admitted with TC, of whom 1.2% experienced in-hospital mortality. Median age was 67 years, with 91.5% being female. Among survivors, 10.3% were readmitted within 1 month; 25% of the initial 1-month readmissions occurred within 4 days, 50% within 10 days, and 75% within 20 days from discharge. The most common etiologies for readmission were cardiac (26%), respiratory (16%), and gastrointestinal (11%) causes. Heart failure was the most common cardiac etiology. Significant predictors of increased 1-month readmission included systemic thromboembolic events, length of stay ≥3 days, and underlying psychoses. Obesity and private insurance predicted lower 1-month readmission. The annual national cost impact for index admission and 1-month readmissions was ≈$112 million. Recurrent TC was seen among 1.9% of patients readmitted within 6 months.

conclusionsThough the overall rate of 1-month readmission following TC is low, associated economic burden from readmission is still significant. Patients are readmitted mostly for noncardiac causes. Readmission for another episode of TC within 6 months was uncommon.

Indexed as

Risk AssessmentAgedDatabases, FactualDisease ProgressionFemaleFollow-Up StudiesHeart FailureHospital MortalityHumansMaleMiddle AgedPatient ReadmissionRetrospective StudiesRisk FactorsSurvival RateTakotsubo CardiomyopathyEtiologiesPredictorsReadmissionTakotsuboThromboembolism

Identifiers

PMID29726021
PMCPMC6489807

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.