SynthesisWorld journal of urology2018
Erectile dysfunction and risk of cardiovascular and all-cause mortality in the general population: a meta-analysis of cohort studies.
Synthesis in World journal of urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use.Nutrients · 2023Pooled it
- Association of erectile dysfunction and cardiovascular disease: an umbrella review of systematic reviews and meta-analyses.BJU international · 2021Pooled it
- People smoke for nicotine, but lose sexual and reproductive health for tar: a narrative review on the effect of cigarette smoking on male sexuality and reproduction.Journal of endocrinological investigation · 2020Pooled it
- Association of erectile dysfunction with all-cause and cardiovascular mortality in US men: findings from NHANES 2001-2004 with 16-year follow-up.International journal of impotence research · 2025Article
- Potential utility of the triglyceride-glucose index as a predictor of erectile dysfunction and its severity: a cross-sectional, case-control study.Scientific reports · 2025Article
- 2024 Guidelines of the Taiwan Society of Cardiology on the Primary Prevention of Atherosclerotic Cardiovascular Disease --- Part II.Acta Cardiologica Sinica · 2024Article
- Association between erectile dysfunction and the prevalence and prognosis of hyperglycemia in adults in the USA based on NHANES 2001-2004.Scientific reports · 2024Article
- Can atherogenic indices and the triglyceride-glucose index be used to predict erectile dysfunction?Sexual medicine · 2023Article
- Can Erectile Dysfunction Severity Predict Major Adverse Cardiovascular Events in Men Undergoing Dialysis? A Prospective Cohort Study.The world journal of men's health · 2023Article
- Arterial stiffness and the non-dipping pattern in type 1 diabetes males with and without erectile dysfunction.Scientific reports · 2023Article
- Sexual dysfunction is highly prevalent in male survivors of malignant lymphoma.Sexual medicine · 2023Article
- Association of BMI with erectile dysfunction: A cross-sectional study of men from an andrology clinic.Frontiers in endocrinology · 2023Article
- Acromegaly and male sexual health.Reviews in endocrine & metabolic disorders · 2022Review
- Interactions between erectile dysfunction, cardiovascular disease and cardiovascular drugs.Nature reviews. Cardiology · 2022Review
- Association Between Penile Color Doppler Ultrasonography and Cardiorespiratory Fitness in Patients With Vascular Erectile Dysfunction.Sexual medicine · 2021Article
- Physical activity as an adjunct treatment for erectile dysfunction.Nature reviews. Urology · 2019Review
- Misdiagnosis And Undertreatment Of Erectile Dysfunction In The Portuguese Primary Health Care.Sexual medicine · 2019Article
- Topic issue: men's health in 2019.World journal of urology · 2019Article
- Relative Fat Mass, A Better Predictor of Erectile Dysfunction: Insights From the NHANES 2001-2004.American journal of men's healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
purposeStudies on the association of erectile dysfunction (ED) with cardiovascular or all-cause mortality have yielded conflicting findings. We conducted this meta-analysis to evaluate the association of ED with cardiovascular or all-cause mortality in the general population.
methodsPubmed and Embase databases were searched for prospective studies that evaluated the association of ED with cardiovascular or all-cause mortality in the general population up to 15 December, 2017. The overall combined risk ratio (RR) and 95% confidence intervals (CI) were pooled for the men with or without ED.
resultsA total of 7 studies involving 111,440 participants were included in the meta-analysis. When compared to the men with or without ED, the overall pooled RR was 1.24 (95% CI 1.11-1.39) for all-cause mortality and 1.11 (95% CI 0.92-1.35) for cardiovascular mortality. Subgroup analyses indicated that only men with severe ED significantly increased all-cause mortality risk (RR 1.58; 95% CI 1.37-1.82), but not in the mild (RR 1.07; 95% CI 0.93-1.24) ED and the moderate (RR 1.16; 95% CI 1.00-1.35) ED.
conclusionsThis meta-analysis suggests that severe ED is significantly associated with increased all-cause mortality in the general population. However, the association of ED with cardiovascular mortality should be further investigated.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.