Evidence map›Paper›PMID 29725716›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2018

Christian Schmidkonz, Michael Cordes, Daniela Schmidt, Tobias Bäuerle, Theresa Ida Goetz, Michael Beck, Olaf Prante, Alexander Cavallaro, Michael Uder, Bernd Wullich and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it, 112 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Journal of racial and ethnic health disparities · 2026
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  4. PSMA-PET-derived distance features as biomarkers for predicting outcomes in primary prostate cancer post-radical prostatectomy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
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  5. Biodistribution and dosimetry of [European journal of nuclear medicine and molecular imaging · 2025
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  6. Role ofBMC cancer · 2025
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  7. Diagnostic value ofCancer biology & therapy · 2024
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  8. Article
  9. Article
  10. Article
  11. Pre-treatmentMolecular imaging and biology · 2024
    Article
  12. Deep learning-based whole-body characterization of prostate cancer lesions on [European journal of nuclear medicine and molecular imaging · 2024
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  13. Article
  14. Review
  15. Review
  16. Early biochemical and radiographic response after one cycle of [European journal of nuclear medicine and molecular imaging · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Christian SchmidkonzClinic of Nuclear Medicine, University Hospital Erlangen, Erlangen, Germany. christian.schmidkonz@uk-erlangen.de.ORCID 0000-0002-1988-0058
Michael CordesClinic of Nuclear Medicine, University Hospital Erlangen, Erlangen, Germany.
Daniela SchmidtClinic of Nuclear Medicine, University Hospital Erlangen, Erlangen, Germany.
Tobias BäuerleInstitute of Radiology, University Hospital Erlangen, Erlangen, Germany.
Theresa Ida GoetzClinic of Nuclear Medicine, University Hospital Erlangen, Erlangen, Germany.
Michael BeckClinic of Nuclear Medicine, University Hospital Erlangen, Erlangen, Germany.
Olaf PranteClinic of Nuclear Medicine, University Hospital Erlangen, Erlangen, Germany.
Alexander CavallaroInstitute of Radiology, University Hospital Erlangen, Erlangen, Germany.
Michael UderInstitute of Radiology, University Hospital Erlangen, Erlangen, Germany.
Bernd WullichDepartment of Urology and Pediatric Urology, University Hospital Erlangen, Erlangen, Germany.
Peter GoebellDepartment of Urology and Pediatric Urology, University Hospital Erlangen, Erlangen, Germany.
Torsten KuwertClinic of Nuclear Medicine, University Hospital Erlangen, Erlangen, Germany.
Philipp RittClinic of Nuclear Medicine, University Hospital Erlangen, Erlangen, Germany.
Universitätsklinikum Erlangen · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed at evaluating the role of

methodsA total of 142 patients with biochemical recurrence of prostate cancer underwent PET/CT with [

resultsPSMA-TV and TL-PSMA demonstrated a significant correlation with serum PSA levels (P < 0.0001) and TL-PSMA was significantly different for different Gleason scores. The agreement rate between TL-PSMA derived from PET and biochemical response was 87% (95% confidence interval, 0.66-0.97; Cohen's κ = 0.78; P < 0.01) and, thus, higher than for SUVmax, which was 74% (95% CI, 0.52-0.90; κ = 0.55; P < 0.01). Furthermore, agreement with PSA was higher for TL-PSMA and SUVmax than for CT-based response evaluation. Discordant findings between PET and CT were most likely due to limitations of CT and RECIST in rating small lymph nodes as metastases, as well as bone involvement, which was sometimes not detectable in CT.

conclusion

Indexed as

OligopeptidesPositron Emission Tomography Computed TomographyTumor BurdenAgedAged, 80 and overEdetic AcidGallium IsotopesGallium RadioisotopesHumansMaleMiddle AgedProstate-Specific AntigenProstatic NeoplasmsTreatment OutcomeEdetic Acidgallium 68 PSMA-11Gallium IsotopesGallium RadioisotopesOligopeptidesProstate-Specific Antigen68Ga-PSMA-11 PET/CTMetabolic tumor parametersProstate cancerTreatment responseWhole-body tumor burden

Identifiers

PMID29725716
OpenAlexW2801867624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.