SynthesisSkeletal radiology2018
Diagnostic accuracy of dual-energy CT in gout: a systematic review and meta-analysis.
Synthesis in Skeletal radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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Who cites it
33 citing papers in PubMed, 61 citations in OpenAlex.
- Review
- An Unusual Initial Presentation of Gout at the Wrist: Extensor Tenosynovitis With Dual-Energy CT and MRI Correlation.Cureus · 2025Article
- Diagnostic accuracy of dual energy computed tomography for suspected pyogenic spondylodiscitis.Scientific reports · 2025Article
- Imaging of gout: an atlas.Rheumatology advances in practice · 2025Review
- Advanced imaging techniques in crystal arthritis.Therapeutic advances in musculoskeletal disease · 2025Review
- Imaging of lower extremity infections: predisposing conditions, atypical infections, mimics, and differentiating features.Skeletal radiology · 2024Review
- Associations of Changes in Knee Hyaline Cartilage Composition Measured With Dual-Energy Computed Tomography in Gout, Aging and Osteoarthritis.Cartilage · 2024Article
- Assessment of thoracic disc degeneration using dual-energy CT-based collagen maps.European radiology experimental · 2024Article
- Dual-energy CT applications in musculoskeletal disorders.The British journal of radiology · 2024Article
- Pathophysiology and Treatment of Gout Arthritis; including Gout Arthritis of Hip Joint: A Literature Review.Hip & pelvis · 2024Review
- Tophaceous gouty arthritis with spondylolysis: a case report.Journal of surgical case reports · 2023Article
- Dual-Layer Spectral CT as Innovative Imaging Guidance in Lung Biopsies: Could Color-Coded Z-Effective Images Allow More Diagnostic Samplings and Biomarkers Information?Journal of clinical medicine · 2023Article
- Review
- Assessing tophaceous spinal gout treatment response using dual-energy CT as a point-of-care imaging modality: case report.Skeletal radiology · 2023Article
- Spinal gout diagnosis in chiropractic practice: narrative review.The Journal of the Canadian Chiropractic Association · 2023Article
- Dual-Energy-CT for Osteitis and Fat Lesions in Axial Spondyloarthritis: How Feasible Is Low-Dose Scanning?Diagnostics (Basel, Switzerland) · 2023Article
- Gout in the peri-scapular region manifests as paradoxical low back pain.Archives of medical science : AMS · 2023Article
- Virtual monoenergetic images from dual-energy CT: systematic assessment of task-based image quality performance.Quantitative imaging in medicine and surgery · 2022Article
- The role of dual energy computed tomography in the differentiation of acute gout flares and acute calcium pyrophosphate crystal arthritis.Clinical rheumatology · 2022Article
- A Case of Spinal Infectious Osteomyelitis Versus Gout: Advanced Imaging with Dual Energy CT.The Yale journal of biology and medicine · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveDual-energy CT (DECT) is being widely used in suspected gout patients in recent years. Many clinicians tend to use DECT instead of aspiration biopsy in the diagnosis of gout, but its accuracy has shown controversial results. In this systematic review and meta-analysis, we sought to evaluate the accuracy of DECT in the diagnosis of gout. MATERIALS AND
methodsWe performed a systematic review of the literature published in Medline, Embase, PubMed, and Cochrane databases. Studies included are all clinical trials of DECT in the diagnosis of gout. Quality assessment of bias and applicability was conducted using the Quality of Diagnostic Accuracy Studies-2 (QUADAS-2). We recorded sensitivity and specificity of algorithms and calculated positive likelihood ratio (PLR), negative likelihood ratio (NLR) and diagnostic odd ratio (DOR), and respective confidence intervals (CI). The summary receiver operating characteristic curve (sROC) was drawn to get the Cochran Q-index and the area under the curve (AUC).
resultsSeven studies were included in this review and showed high homogeneity. The analysis results presented the pooled sensitivity was 88% (95% CI 84-90%) and specificity was 90% (95% CI 85-93%). Then, we figured out that the pooled PLR was 8.48 (95% CI 5.89-12.22) and NLR was 0.10 (95% CI 0.04-0.24) respectively. In addition, Cochran-Q was 0.90 and AUC was 0.9565 in sROC curve.
conclusionsDECT showed relatively high sensitivity and specificity in the diagnosis of gout. Synthetically considering these DECT abnormalities could improve the diagnostic sensitivity. More rigorous and standardized studies are still needed to support these findings.
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