ReviewKidney international reports2018
Acute Kidney Injury in Pregnancy: The Changing Landscape for the 21st Century.
Review in Kidney international reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed.
- Renal Challenges in Pregnancy: Clinical Spectrum and Outcomes of Acute Kidney Injury in a Tertiary Care Center.Cureus · 2026Article
- Acute kidney injury associated with acute fatty liver of pregnancy: An update on a rare clinical entity.World journal of nephrology · 2025Review
- Prognostic significance of liver affliction in pregnancy related acute kidney injury in an Egyptian cohort.Scientific reports · 2025Article
- Pregnancy-associated acute kidney injury as an important driver of chronic kidney disease in females in developing countries: A systematic review.Maternal health, neonatology and perinatology · 2025Review
- Article
- Pharmacologic and endotoxic reprogramming of renal vasodilatory, inflammatory, and apoptotic blemishes in weaning preeclamptic rats.Scientific reports · 2025Article
- Second Trimester Kidney Function and Adverse Pregnancy Outcomes among Patients with Lupus.Kidney360 · 2025Article
- Maternal Mortality due to Pregnancy-Related Acute Kidney Injury (PRAKI); A Study of the Epidemiological Factors and Possible Solutions.Journal of obstetrics and gynaecology of India · 2025Article
- Study Design of a Nationwide Network Indian Cohort of Pregnancy-Associated Acute Kidney Injury (iPRAKI NET).Kidney international reports · 2025Article
- Maternal and Fetal Prognosis in Pregnant Women with Renal Disease Associating Urinary Tract Infection.Maedica · 2024Article
- Article
- Urinary Nephrin: A Potential Biomarker of Early Glomerular Injury in a Cohort of Pregnant Women Attending Routine Antenatal Care Services.International journal of nephrology · 2024Article
- Acute Kidney Injury: Magnitude and Predictors of Maternal Outcomes among Pre-Eclamptic and Eclamptic Women in Mwanza, Tanzania.The East African health research journal · 2024Article
- Use of Renal Replacement Therapy in Pregnant Women with Acute Kidney Injury or Chronic Kidney Disease: A Systematic Review.Acta medica Philippina · 2024Article
- Miscarriage-Related Acute Kidney Injury: A Case Report.International medical case reports journal · 2024Article
- Characteristics and Outcomes of Patients With Pregnancy-Related End-Stage Kidney Disease.JAMA network open · 2023Article
- Assessment of Kidney Impairment and Related Risk Factors in Pregnant Women Attending the University Center for Public Health and Rango Health Centers in the Southern Province of Rwanda.Rwanda journal of medicine and health sciences · 2023Article
- Clinical characteristics and prognosis of pregnancy-related acute kidney injury: a case series study.International urology and nephrology · 2023Article
- Physiology of Pregnancy-Related Acute Kidney Injury.Comprehensive Physiology · 2023Article
- Etiology of Pregnancy-related Acute Kidney Injury among Obstetric Patients in India: A Systematic Review.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pregnancy-related acute kidney injury (Pr-AKI) remains a large public health problem, with decreasing incidences in developing countries but seemingly increasing incidences in the United States and Canada. These epidemiologic changes are reflective of the advances in medical and obstetric care, as well as changes in underlying maternal risk factors. The risk factors associated with advanced maternal age, such as hypertension, diabetes, chronic kidney disease, and those associated with reproductive technologies such as multiple gestations, are increasing. Traditional causes of Pr-AKI, such as septic abortions and puerperal sepsis, have been replaced by hypertensive diseases, such as preeclampsia and thrombotic microangiopathies comprising thrombotic thrombocytopenic purpura (TTP) and atypical hemolytic uremic syndrome (aHUS). In this review, we discuss the global impact of Pr-AKI on maternal and fetal outcomes, the predominant etiologies, and key clinical features to distinguish diagnoses, such as preeclampsia/hemolysis elevated liver function test and low platelet (HELLP) syndrome, acute fatty liver disease of pregnancy (AFLP), and other thrombotic microangiopathies. New insights into the pathogenesis of preeclampsia, TTP/aHUS, and AFLP that have unearthed possible therapeutic targets are summarized. We also delve into special consideration needed to give to pyelonephritis and postobstructive causes of Pr-AKI. With each diagnosis, we offer the latest treatment recommendations, such as the positive reports from the use of eculizumab to treat aHUS. In the end, we hope to arm the clinician with the best tools to understand and address this morbid problem that does not seem to be disappearing.
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Registered trials
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