ArticleMolecular and clinical oncology2018
Non-invasive imaging of actinic cheilitis and squamous cell carcinoma of the lip.
Article in Molecular and clinical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 56 citations in OpenAlex.
- Global burden and trends of common head and neck cancers between 1990 and 2021: findings from the Global Burden of Disease Study 2021.BMC oral health · 2025Article
- Squamous cell carcinoma of lower lip: the results of wide V-shaped resection.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2023Article
- Actinic cheilitis or squamous cell carcinoma of the lip? Practical recommendations on how to avoid a trap.Revista da Associacao Medica Brasileira (1992) · 2022Article
- Persistent Changes of Peripheral Blood Lymphocyte Subsets in Patients with Oral Squamous Cell Carcinoma.Healthcare (Basel, Switzerland) · 2022Article
- Artificial Intelligence-Based Approaches to Reflectance Confocal Microscopy Image Analysis in Dermatology.Journal of clinical medicine · 2022Review
- Actinic Cheilitis - From Risk Factors to Therapy.Frontiers in medicine · 2022Review
- Editorial: Recent advances in keratinocyte carcinomas: From molecular mechanisms to clinical perspectives.Frontiers in medicine · 2022Article
- High serum level of interleukin-6 is linked with dyslipidemia in oral lichen planus.Experimental and therapeutic medicine · 2021Article
- Molecular markers associated with potentially malignant oral lesions (Review).Experimental and therapeutic medicine · 2021Review
- [New diagnostic classification of cheilitis and its clinical diagnostic pathway].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2021Article
- In vivo reflectance confocal microscopy for the diagnosis of scabies.BMJ case reports · 2021Article
- Impact of histological subtype on the response to chemoradiation in locally advanced cervical cancer and the possible role of surgery.Experimental and therapeutic medicine · 2021Article
- Treatment trends in oral lichen planus and oral lichenoid lesions (Review).Experimental and therapeutic medicine · 2020Review
- Evaluation of effect of a vitamin-based barrier cream on the clinical severity of actinic cheilitis: A preliminary study.Journal of clinical and experimental dentistry · 2020Article
- Penile carcinoma and HPV infection (Review).Experimental and therapeutic medicine · 2020Review
- Use of imaging techniques for melanocytic naevi and basal cell carcinoma in integrative analysis (Review).Experimental and therapeutic medicine · 2020Review
- In Vivo Reflectance Confocal Microscopy-Diagnostic Criteria for Actinic Cheilitis and Squamous Cell Carcinoma of the Lip.Journal of clinical medicine · 2020Article
- Venous thromboembolism in cancer patients: Still looking for answers.Experimental and therapeutic medicine · 2019Review
- Cisplatin effect on head and neck squamous cell carcinoma cells is modulated by ERK1/2 protein kinases.Experimental and therapeutic medicine · 2019Article
- Therapeutic options in patients with biochemical recurrence after radical prostatectomy.Experimental and therapeutic medicine · 2019Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An early diagnosis is of overwhelming importance for the management and prognosis of mucocutaneous cancer. Actinic cheilitis (AC), defined by the clonal expansion of genomically unstable keratinocytes, is the most common potentially malignant lesion affecting the lips. Squamous cell carcinoma (SCC) is the most frequent oral malignancy, and there is strong evidence that the majority of the SCCs of the lip originate from AC. There is considerable difficulty in discerning between dysplasia and invasive carcinomas solely on a clinical basis. Although dermoscopy has become an essential tool for skin tumor evaluation, reflectance confocal microscopy (RCM) is a non-invasive imaging technology that has proved itself extremely useful in the diagnosis and monitoring of several skin diseases, including AC and SCC. The present study aimed to re-emphasize the usefulness of RCM in the early detection of malignant transformation, using AC and SCC of the lips as working examples. Due to the apparent innocuousness of AC for numerous patients, it is not possible to overstress the importance of a correct and early diagnosis, proper treatment and long-term patient follow-up as being essential for preventing the progression to lip SCC, or for its timely diagnosis.
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