Evidence map›Paper›PMID 29725442›Full record

ArticleOncology letters2018

miR-486-5p regulates the migration and invasion of colorectal cancer cells through targeting PIK3R1.

Yuhao Zhang, Jun Fu, Zhijin Zhang, Huanlong Qin

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 40 citations in OpenAlex.

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  17. MicroRNA-486-5p Suppresses Lung CancerFrontiers in oncology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yuhao ZhangDepartment of General Surgery, The Affiliated Shanghai No. 10 People's Hospital, Nanjing Medical University, Shanghai 200072, P.R. China.
Jun FuDepartment of General Surgery, Shanghai No. 8 People's Hospital, Shanghai 200235, P.R. China.
Zhijin ZhangDepartment of General Surgery, Shanghai No. 8 People's Hospital, Shanghai 200235, P.R. China.
Huanlong QinDepartment of General Surgery, The Affiliated Shanghai No. 10 People's Hospital, Nanjing Medical University, Shanghai 200072, P.R. China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to investigate the function of microRNA (miR)-486-5p in colorectal cancer (CRC). Tumor and adjacent normal mucosal tissue samples were collected from patients with CRC. Differences in the expression levels of miR-486-5p between tumor tissues and adjacent normal mucosal tissues were examined using reverse transcription-quantitative polymerase chain reaction. The results demonstrated that miR-486-5p was significantly decreased in tumor tissues compared with the adjacent normal mucosal tissues. Additionally,

Indexed as

colorectal cancermicroRNA-486-5pphosphatidylinositol 3-kinase regulatory subunit 1

Identifiers

PMID29725442
PMCPMC5920487
OpenAlexW2790699258

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.