Evidence map›Paper›PMID 29725334›Full record

ReviewFrontiers in immunology2018

Humanized Mouse Models for the Study of Human Malaria Parasite Biology, Pathogenesis, and Immunity.

Nana K Minkah, Carola Schafer, Stefan H I Kappe

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  5. Article
  6. Review
  7. Review
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  9. Review
  10. Article
  11. Article
  12. IdentifyingResearch square · 2024
    Article
  13. Article
  14. Single-cell analyses of polyclonalResearch square · 2024
    Article
  15. Article
  16. A Monocytic Barrier to the Humanization of Immunodeficient Mice.Current stem cell research & therapy · 2024
    Review
  17. Article
  18. Cultivation of Asexual Intraerythrocytic Stages ofPathogens (Basel, Switzerland) · 2023
    Review
  19. AIM2 sensors mediate immunity toProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  20. Hastening Progress inMicroorganisms · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nana K MinkahCenter for Infectious Disease Research, Seattle, WA, United States.
Carola SchaferCenter for Infectious Disease Research, Seattle, WA, United States.
Stefan H I KappeCenter for Infectious Disease Research, Seattle, WA, United States.

Funding

Innate immune responses to malaria liver stage infectionR01AI114699 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI KAPPE, STEFAN HI · 2015 to 2019
$2.5M
NIAID NIH HHS R01 AI114699
6 · The paper itself

Abstract

Malaria parasite infection continues to inflict extensive morbidity and mortality in resource-poor countries. The insufficiently understood parasite biology, continuously evolving drug resistance and the lack of an effective vaccine necessitate intensive research on human malaria parasites that can inform the development of new intervention tools. Humanized mouse models have been greatly improved over the last decade and enable the direct study of human malaria parasites

Indexed as

Disease Models, AnimalAnimalsBiomedical ResearchErythrocytesHumansLife Cycle StagesMalariaMalaria VaccinesMiceMice, TransgenicPlasmodiumSporozoitesMalaria VaccinesFRG human hepatocytehuman immune system micehumanized mouse modelsmalaria vaccinesPlasmodium falciparum

Identifiers

PMID29725334
PMCPMC5917005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.