Evidence map›Paper›PMID 29725297›Full record

ArticleFrontiers in pharmacology2018

1-Deoxynojirimycin (DNJ) Ameliorates Indomethacin-Induced Gastric Ulcer in Mice by Affecting NF-kappaB Signaling Pathway.

Xuehua Piao, Shuangdi Li, Xiaodan Sui, Lianyi Guo, Xingmei Liu, Hongmei Li, Leming Gao, Shusheng Cai, Yanrong Li, Tingting Wang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Chemical Composition and Antiulcer Effects of Filipendula palmata in Mice.Plant foods for human nutrition (Dordrecht, Netherlands) · 2025
    Article
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  6. Gastroprotective effects ofJournal of traditional and complementary medicine · 2023
    Article
  7. Article
  8. Protective Application ofAnimals : an open access journal from MDPI · 2022
    Review
  9. Gastroprotective Effect ofAntioxidants (Basel, Switzerland) · 2022
    Article
  10. Molecular Mechanism ofBiomolecules · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Preventive Effect ofFoods (Basel, Switzerland) · 2019
    Article
  17. Article
  18. Pretreatment withFood & nutrition research · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Xuehua PiaoDepartment of Traditional Chinese Medicine, The First Affiliated Hospital, Jinzhou Medical University, Jinzhou, China.
Shuangdi LiHeart Disease Center, The Affiliated Hospital of Changchun University of Traditional Chinese Medicine, Changchun, China.
Xiaodan SuiDepartment of Hepatology, The Affiliated Hospital of Changchun University of Traditional Chinese Medicine, Changchun, China.
Lianyi GuoDepartment of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Xingmei LiuDepartment of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Hongmei LiDepartment of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Leming GaoSchool of Stomatology, 2nd Dental Center, Peking University, Beijing, China.
Shusheng CaiDepartment of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Yanrong LiDepartment of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Tingting WangDepartment of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Baohai LiuDepartment of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Jinzhou Medical University · CNChangchun University · CNChangchun University of Chinese Medicine · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric ulcer (GU) is a main threat to public health. 1-Deoxynojirimycin (DNJ) has antioxidant and anti-inflammatory properties and may prevent GU but related mechanism remains unclear. DNJ was extracted from the supernatants of

Indexed as

DNJgastric ulcerationmouseNF-κB signaling pathwayprostaglandin E2

Identifiers

PMID29725297
PMCPMC5917448
OpenAlexW2800112831

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.