Evidence map›Paper›PMID 29725004›Full record

ArticleNature communications2018

CCDC102B confers risk of low vision and blindness in high myopia.

Yoshikatsu Hosoda, Munemitsu Yoshikawa, Masahiro Miyake, Yasuharu Tabara, Noriaki Shimada, Wanting Zhao, Akio Oishi, Hideo Nakanishi, Masayuki Hata, Tadamichi Akagi and 11 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Identification of a Novel Frameshift Variant ofJournal of clinical medicine · 2023
    Article
  14. Article
  15. Review
  16. Observational
  17. Article
  18. Myopia Genetics and Heredity.Children (Basel, Switzerland) · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 2 countries.

Yoshikatsu HosodaDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, 6068507, Japan.
Munemitsu YoshikawaDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, 6068507, Japan.
Masahiro MiyakeDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, 6068507, Japan.
Yasuharu TabaraCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, 6068503, Japan.
Noriaki ShimadaDepartment of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, 1138510, Japan.
Wanting ZhaoSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, 168751, Singapore.
Akio OishiDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, 6068507, Japan.
Hideo NakanishiDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, 6068507, Japan.
Masayuki HataDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, 6068507, Japan.
Tadamichi AkagiDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, 6068507, Japan.
Sotaro OotoDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, 6068507, Japan.
Natsuko NagaokaDepartment of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, 1138510, Japan.
Yuxin FangDepartment of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, 1138510, Japan.
Nagahama Study group
Kyoko Ohno-MatsuiDepartment of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, 1138510, Japan.
Ching-Yu ChengSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, 168751, Singapore.
Seang Mei SawSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, 168751, Singapore.
Ryo YamadaCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, 6068503, Japan.
Fumihiko MatsudaCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, 6068503, Japan.
Akitaka TsujikawaDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, 6068507, Japan.
Kenji YamashiroDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, 6068507, Japan. yamashro@kuhp.kyoto-u.ac.jp.ORCID http://orcid.org/0000-0001-9354-8558
Kyoto University · JPTokyo Medical and Dental University · JPNational University of Singapore · SGSingapore National Eye Center · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of high myopia is increasing worldwide with myopic maculopathy, a complication of myopia, often progressing to blindness. Our two-stage genome-wide association study of myopic maculopathy identifies a susceptibility locus at rs11873439 in an intron of CCDC102B (P = 1.77 × 10

Indexed as

AdultAgedAsian PeopleBlindnessChoroidCohort StudiesCytoskeletal ProteinsFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansJapanMacula LuteaMaleMiddle AgedMyopiaCCDC102B protein, humanCytoskeletal Proteins

Identifiers

PMID29725004
PMCPMC5934384
OpenAlexW2800275879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.