Evidence map›Paper›PMID 29724987›Full record

ArticleBiomedicines2018

Platelet-Rich Plasma (PRP) Rinses for the Treatment of Non-Responding Oral Lichen Planus: A Case Report.

Elisabetta Merigo, Aldo Oppici, Anna Parlatore, Luigi Cella, Fabio Clini, Matteo Fontana, Carlo Fornaini

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Elisabetta MerigoDentistry, Special Needs and Maxillo-Facial Surgery Unit, Hospital "Guglielmo da Saliceto", 29100 Piacenza, Italy. elisabetta.merigo@gmail.com.ORCID 0000-0002-7437-8511
Aldo OppiciDentistry, Special Needs and Maxillo-Facial Surgery Unit, Hospital "Guglielmo da Saliceto", 29100 Piacenza, Italy. a.oppici@ausl.pc.it.
Anna ParlatoreTranfusional Unit, Hospital "Guglielmo da Saliceto", 29100 Piacenza, Italy. a.parlatore@ausl.pc.it.
Luigi CellaDentistry, Special Needs and Maxillo-Facial Surgery Unit, Hospital "Guglielmo da Saliceto", 29100 Piacenza, Italy. l.cella@ausl.pc.it.
Fabio CliniDentistry, Special Needs and Maxillo-Facial Surgery Unit, Hospital "Guglielmo da Saliceto", 29100 Piacenza, Italy. f.clini@ausl.pc.it.
Matteo FontanaDentistry, Special Needs and Maxillo-Facial Surgery Unit, Hospital "Guglielmo da Saliceto", 29100 Piacenza, Italy. m.fontana@ausl.pc.it.
Carlo FornainiDentistry, Special Needs and Maxillo-Facial Surgery Unit, Hospital "Guglielmo da Saliceto", 29100 Piacenza, Italy. carlo@fornainident.it.ORCID 0000-0001-7566-060X
Guglielmo da Saliceto Hospital · ITUniversité Côte d'Azur · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Platelet-rich plasma (PRP) has been proposed for different applications in the medical field and in maxillofacial surgery thanks to its many growth factors, such as epidermal growth factor (EGF), fibroblast growth factor (FGF), and keratinocyte growth factor (KGF). Oral lichen planus (OLP) is a disease that affects the oral mucosa in a chronic way. This disease frequently worsens the quality of life of patients, particularly when clinical manifestations are of the erythematous or erosive/ulcerative type. The properties of PRP that are supported by scientific literature in both oral medicine and other medical fields have suggested the introduction of PRP in clinical practice for the medical treatment of different soft tissues diseases, such as when OLP patients do not respond to conventional therapies, or when conventional treatments have some contraindications or side effects. The aim of this work is to describe the use of PRP used as an oral rinse for the treatment of a patient diagnosed as affected by OLP at the Dentistry, Special Needs and Maxillo-Facial Surgery Unit of the Hospital of Piacenza. PRP protocol was started after the failure of conventional therapies based on the use of topical and systemic corticosteroids, hydroxychloroquine, and low-level laser therapy applications.

Indexed as

Oral Lichen Planusplatelet-rich plasma (PRP)wound healing

Identifiers

PMID29724987
PMCPMC5874672
OpenAlexW2789254718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.