Evidence map›Paper›PMID 29724820›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2018

Temporal and Spatial Post-Transcriptional Regulation of Zebrafish

Tamjid A Chowdhury, Chris Koceja, Shahram Eisa-Beygi, Benjamin P Kleinstiver, Suresh N Kumar, Chien-Wei Lin, Keguo Li, Shubhangi Prabhudesai, J Keith Joung, Ramani Ramchandran

Open access · bronzeAbstract readVideo-Audio Media
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

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  6. Emerging Roles of RNA-Binding Proteins in Neurodevelopment.Journal of developmental biology · 2022
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  12. Annual Report on Sex in Preclinical Studies:Arteriosclerosis, thrombosis, and vascular biology · 2020
    Review
  13. Functional Genomics and CRISPR Applied to Cardiovascular Research and Medicine.Arteriosclerosis, thrombosis, and vascular biology · 2019
    Article
  14. Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Tamjid A ChowdhuryObstetrics and Gynecology (T.A.C., K.L., R.R.).
Chris KocejaFrom the Division of Neonatology, Department of Pediatrics (C.K., K.L., S.P., R.R.).
Shahram Eisa-BeygiDepartment of Radiology (S.E.-B.).
Benjamin P KleinstiverMolecular Pathology Unit, Massachusetts General Hospital, Charlestown (B.P.K., J.K.J.).
Suresh N KumarDepartment of Pathology (S.N.K.).
Chien-Wei LinDivision of Biostatistics (C.-W.L.), Developmental Vascular Biology Program, Children's Research Institute, Medical College of Wisconsin, Milwaukee.
Keguo LiFrom the Division of Neonatology, Department of Pediatrics (C.K., K.L., S.P., R.R.).
Shubhangi PrabhudesaiFrom the Division of Neonatology, Department of Pediatrics (C.K., K.L., S.P., R.R.).
J Keith JoungMolecular Pathology Unit, Massachusetts General Hospital, Charlestown (B.P.K., J.K.J.).
Ramani RamchandranFrom the Division of Neonatology, Department of Pediatrics (C.K., K.L., S.P., R.R.) rramchan@mcw.edu.
Massachusetts General Hospital · USChildren's Hospital of Wisconsin · USNorwegian Womens Public Health Association · NOS.P.E.C.I.E.S. · US

Funding

Targeting DUSP-5 to Treat Vascular AnomaliesR01HL112639 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI RAMCHANDRAN, RAMANI · 2012 to 2016
$2.6M
Delta like-4 long non-coding RNA function in angiogenesis and vascular anomaliesR01HL123338 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI RAMCHANDRAN, RAMANI · 2015 to 2018
$1.8M
NHLBI NIH HHS R01 HL123338
6 · The paper itself

Abstract

objectiveTie1 (tyrosine kinase containing immunoglobulin and epidermal growth factor homology 1), an endothelial and hematopoietic cell-specific receptor tyrosine kinase, is an important regulator of angiogenesis and critical for maintaining vascular integrity. The post-transcriptional regulation of APPROACH AND

resultsThrough in vitro and in vivo ribonucleoprotein binding studies, we demonstrated that

conclusionsWe identified a novel mode of temporal and spatial post-transcriptional regulation of

Indexed as

RNA Processing, Post-TranscriptionalAnimalsAnimals, Genetically ModifiedBlood VesselsBrainELAV-Like Protein 1Gene Expression Regulation, DevelopmentalGene Expression Regulation, EnzymologicNeovascularization, PhysiologicReceptor, TIE-1RNA, AntisenseRNA, Long NoncodingRNA, MessengerTime FactorsZebrafishZebrafish ProteinsELAV-Like Protein 1Receptor, TIE-1RNA, AntisenseRNA, Long NoncodingRNA, Messengertie1 protein, zebrafishZebrafish ProteinsantisenseElavl1endotheliumRNAzebrafish

Identifiers

PMID29724820
PMCPMC6023729
OpenAlexW2802940065

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.