Evidence map›Paper›PMID 29724796›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

GAD65 Promoter Polymorphism rs2236418 Modulates Harm Avoidance in Women via Inhibition/Excitation Balance in the Rostral ACC.

Lejla Colic, Meng Li, Liliana Ramona Demenescu, Shija Li, Iris Müller, Anni Richter, Gusalija Behnisch, Constanze I Seidenbecher, Oliver Speck, Björn H Schott and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

  1. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
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  7. The potential ofPsychopharmacology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Lejla ColicCANLAB, 39120 Magdeburg, Germany.
Meng LiCANLAB, 39120 Magdeburg, Germany.
Liliana Ramona DemenescuCANLAB, 39120 Magdeburg, Germany.
Shija LiKey Laboratory of Brain Functional Genomics (MOE&STCSM), Shanghai Changning-ECNU Mental Health Center, School of Psychology and Cognitive Science, East China Normal University, Shanghai, China.
Iris MüllerDepartment of Genetics and Molecular Neurobiology, Institute of Biology, Otto von Guericke University of Magdeburg, 39120 Magdeburg, Germany.ORCID 0000-0001-7799-358X
Anni RichterLeibniz Institute for Neurobiology, 39118 Magdeburg, Germany.
Gusalija BehnischLeibniz Institute for Neurobiology, 39118 Magdeburg, Germany.
Constanze I SeidenbecherLeibniz Institute for Neurobiology, 39118 Magdeburg, Germany.
Oliver SpeckLeibniz Institute for Neurobiology, 39118 Magdeburg, Germany.
Björn H SchottLeibniz Institute for Neurobiology, 39118 Magdeburg, Germany.ORCID 0000-0002-8237-4481
Oliver StorkDepartment of Genetics and Molecular Neurobiology, Institute of Biology, Otto von Guericke University of Magdeburg, 39120 Magdeburg, Germany.ORCID 0000-0003-4285-7507
Martin WalterCANLAB, 39120 Magdeburg, Germany, martin.walter@med.ovgu.de.
Center for Behavioral Brain Sciences · DEKlinikum Magdeburg · DELeibniz Institute for Neurobiology · DEEast China Normal University · CNGerman Center for Neurodegenerative Diseases · DEMax Planck Institute for Biological Cybernetics · DEOtto-von-Guericke-Universität Magdeburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anxiety disorders are common and debilitating conditions with higher prevalence in women. However, factors that predispose women to anxiety phenotypes are not clarified. Here we investigated potential contribution of the single nucleotide polymorphism rs2236418 in

Indexed as

AdultAvoidance LearningBrain MappingFemaleGenotypeGlutamate DecarboxylaseGyrus CinguliHumansMagnetic Resonance ImagingMalePersonalityPolymorphism, GeneticPolymorphism, Single NucleotidePromoter Regions, GeneticYoung AdultGlutamate Decarboxylaseglutamate decarboxylase 2anxiety endophenotypesfMRIGABA/glutamateharm avoidancesex differences

Identifiers

PMID29724796
PMCPMC6705942
OpenAlexW2802875397

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.