Evidence map›Paper›PMID 29724756›Full record

ArticleDevelopment (Cambridge, England)2018

Modulation of F-actin dynamics by maternal Mid1ip1L controls germ plasm aggregation and furrow recruitment in the zebrafish embryo.

Celeste Eno, Francisco Pelegri

Abstract read
In one paragraph

Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Tools to Image Germplasm Dynamics During Early Zebrafish Development.Frontiers in cell and developmental biology · 2021
    Article
  7. Review
  8. Article
  9. Tools of the trade: studying actin in zebrafish.Histochemistry and cell biology · 2020
    Review
  10. Aggregation, segregation, and dispersal of homotypic germ plasm RNPs in the early zebrafish embryo.Developmental dynamics : an official publication of the American Association of Anatomists · 2019
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Celeste EnoLaboratory of Genetics, University of Wisconsin, Madison, WI 53706, USA.
Francisco PelegriLaboratory of Genetics, University of Wisconsin, Madison, WI 53706, USA fjpelegri@wisc.edu.ORCID 0000-0002-0464-7042

Funding

Diversity Supplement: Cytokinesis and RNA segregation in zebrafish developmentR01GM065303 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI PELEGRI, FRANCISCO J · 2002 to 2023
$4.7M
Cytokinesis and RNA Segregation in Zebrafish DevelopmentR56GM065303 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI PELEGRI, FRANCISCO J · 2007 to 2007
$254k
Germ Plasm Aggregation and Compaction in the Early Zebrafish EmbryoF31GM108449 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI ENO, CELESTE CHLOE · 2014 to 2016
$55k
NIGMS NIH HHS F31 GM108449NIGMS NIH HHS R01 GM065303NIGMS NIH HHS R56 GM065303
6 · The paper itself

Abstract

During the early embryonic cell cycles, zebrafish germ plasm ribonucleoparticles (RNPs) gradually multimerize and become recruited to the forming furrows. RNPs multimerization occurs prior to and during furrow initiation, as forming aggregates move outward through their association with the tips of growing interphase astral microtubules. Germ plasm RNPs are also associated with short cortical F-actin. We show that, in embryos mutant for the cytoskeletal regulator

Indexed as

Actin CytoskeletonActinsAnimalsBlastodiscCell MembraneCytoplasmCytoskeletal ProteinsEmbryo, NonmammalianGerm CellsMicrotubulesProtein MultimerizationProtein TransportRibonucleoproteinsZebrafishZebrafish ProteinsActinsCytoskeletal Proteinsmid1ip1l protein, zebrafishRibonucleoproteinsZebrafish ProteinsEmbryoF-actinGerm plasmMicrotubulesMid1ip1LRibonucleoparticlesZebrafish

Identifiers

PMID29724756
PMCPMC6001372

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.