Evidence map›Paper›PMID 29724742›Full record

ArticleBMJ open2018

Light-moderate alcohol consumption and left ventricular function among healthy, middle-aged adults: the HUNT study.

Katalin Gémes, Imre Janszky, Linn Beate Strand, Krisztina D László, Staffan Ahnve, Lars J Vatten, Håvard Dalen, Kenneth J Mukamal

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Katalin GémesDepartment of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
Imre JanszkyDepartment of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
Linn Beate StrandDepartment of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
Krisztina D LászlóDepartment of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
Staffan AhnveDepartment of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
Lars J VattenDepartment of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
Håvard DalenDepartment of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Kenneth J MukamalDepartment of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Karolinska Institutet · SENorwegian University of Science and Technology · NOBeth Israel Deaconess Medical Center · USSt Olav's University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the association between alcohol consumption and left ventricular (LV) function in a population with low average alcohol intake. DESIGN, SETTING AND

participantsA total of 1296 healthy participants, free from cardiovascular diseases, were randomly selected from the third wave of the Norwegian HUNT study (2006-2008) and underwent echocardiography. After validation of the inclusion criteria, 30 participants were excluded due to arrhythmias or myocardial or valvular pathology. Alcohol consumption, sociodemographic and major cardiovascular risk factors were assessed by questionnaires and clinical examination in the HUNT3. General linear models were used to analyse the cross-sectional associations between alcohol intake and LV indices. PRIMARY AND SECONDARY OUTCOME MEASURES: LV functional and structural indices were measured with tissue Doppler and speckle tracking echocardiography.

resultsWe observed no associations between alcohol consumption and multivariable-adjusted LV functional indices. Excluding abstainers who reported regular alcohol consumption 10 years prior to the baseline did not change the results. Alcohol consumption was positively associated with LV mass indices (p<0.01 for linear trend of the means); there was no such association among participants with non-risky drinking characteristics (p=0.67 for linear trend of the means).

conclusionsWe found no clear evidence that light-moderate alcohol consumption is associated with measures of LV function, although our results indicate that consumption, especially when marked by binge drinking, is progressively associated with greater LV mass.

Indexed as

Ventricular Function, LeftAdultAgedAlcohol DrinkingCross-Sectional StudiesEchocardiography, DopplerFemaleHealthy VolunteersHeart VentriclesHumansLinear ModelsMaleMiddle AgedMultivariate AnalysisNorwaySurveys and Questionnairescardiac epidemiologyechocardiographyepidemiologymoderate alcohol consumption

Identifiers

PMID29724742
PMCPMC5988097
OpenAlexW2800868000

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.