Evidence map›Paper›PMID 29724737›Full record

ArticleBMJ open2018

Insulin sensitivity assessed using urine C peptide creatinine ratio (UCPCR) in pregnancy: cross-sectional analysis of an English multiethnic cohort.

Ankica Markoska, Lilian C Mendoza, Rajalakshmi Valaiyapathi, Chloe Thorn, Anne Dornhorst

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. UrinaryNutrients · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ankica MarkoskaDepartment of Investigative Medicine, Faculty of Medicine, Hammersmith Hospital, Imperial College London, London, UK.
Lilian C MendozaDepartment of Investigative Medicine, Faculty of Medicine, Hammersmith Hospital, Imperial College London, London, UK.ORCID 0000-0002-8984-0078
Rajalakshmi ValaiyapathiDepartment of Investigative Medicine, Faculty of Medicine, Hammersmith Hospital, Imperial College London, London, UK.
Chloe ThornDepartment of Investigative Medicine, Faculty of Medicine, Hammersmith Hospital, Imperial College London, London, UK.
Anne DornhorstDepartment of Investigative Medicine, Faculty of Medicine, Hammersmith Hospital, Imperial College London, London, UK.
Hammersmith Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo assess urinary C peptide creatinine ratio (UCPCR) used in a modified Matsuda equation to measure insulin sensitivity (IS) in pregnancy. RESEARCH AND DESIGN

methodsIn this cross-sectional study, two IS measurements were calculated in 73 pregnant women at ~28 weeks of gestation by two separate methods using modified Matsuda equations. The first using the 0 and 120 min serum C peptide concentration during a 75 g oral glucose tolerance test (OGTT) and the second using the 0 and 120 min UCPCR values. The calculated IS measurements from the two methodologies were evaluated using Person's test and linear regression analysis. The relationship between IS

resultsThe IS measured using serum C peptide (IS

conclusionThe UCPCR provides a practical methodology to assess IS and β-cell function in pregnancy.

Indexed as

AdultBlood GlucoseC-PeptideCreatinineCross-Sectional StudiesDiabetes, GestationalFemaleGestational AgeGlucose Tolerance TestHumansInsulin ResistancePredictive Value of TestsPregnancyProspective StudiesRegression AnalysisBlood GlucoseC-PeptideCreatininediabetes In pregnancymaternal medicinephysiology

Identifiers

PMID29724737
PMCPMC5942436
OpenAlexW2801941952

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.