ArticleSensors (Basel, Switzerland)2018
Handheld Real-Time LED-Based Photoacoustic and Ultrasound Imaging System for Accurate Visualization of Clinical Metal Needles and Superficial Vasculature to Guide Minimally Invasive Procedures.
Article in Sensors (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed, 107 citations in OpenAlex.
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- Performance characterization of light-emitting diode array-based photoacoustic computed tomography (LED-PACT).Biomedical optics express · 2025Article
- Temporally delayed, dual-pulse, dual-wavelength photoacoustic imaging (TD-DP-DW-PAI): advancing capabilities of a commercial light-emitting diode-based photoacoustic imaging system with a pulsed laser diode.Biomedical optics express · 2025Article
- LED-based optoacoustic tomography of mice.Journal of biomedical optics · 2025Article
- Learning-based sound speed estimation and aberration correction for linear-array photoacoustic imaging.Photoacoustics · 2024Article
- Ultrasound-guided needle tracking with deep learning: A novel approach with photoacoustic ground truth.Photoacoustics · 2023Article
- Handheld interventional ultrasound/photoacoustic puncture needle navigation based on deep learning segmentation.Biomedical optics express · 2023Article
- Evaluation of temperature-dependent fluctuations in skin microcirculation flow using a light-emitting diode based photoacoustic imaging device.Journal of clinical monitoring and computing · 2023Article
- Full-view LED-based optoacoustic tomography.Photoacoustics · 2023Article
- LED-based photoacoustic imaging for preoperative visualization of lymphatic vessels in patients with secondary limb lymphedema.Photoacoustics · 2023Article
- Spatiotemporal singular value decomposition for denoising in photoacoustic imaging with a low-energy excitation light source.Biomedical optics express · 2022Article
- Enhanced Photoacoustic Visualisation of Clinical Needles by Combining Interstitial and Extracorporeal Illumination of Elastomeric Nanocomposite Coatings.Sensors (Basel, Switzerland) · 2022Article
- Improving needle visibility in LED-based photoacoustic imaging using deep learning with semi-synthetic datasets.Photoacoustics · 2022Article
- Fully Customized Photoacoustic System Using Doubly Q-Switched Nd:YAG Laser and Multiple Axes Stages for Laboratory Applications.Sensors (Basel, Switzerland) · 2022Article
- Acoustic-resolution photoacoustic microscope based on compact and low-cost delta configuration actuator.Ultrasonics · 2022Article
- Review of consensus test methods in medical imaging and current practices in photoacoustic image quality assessment.Journal of biomedical optics · 2021Review
- Annular Fiber Probe for Interstitial Illumination in Photoacoustic Guidance of Radiofrequency Ablation.Sensors (Basel, Switzerland) · 2021Article
- Technical validation studies of a dual-wavelength LED-based photoacoustic and ultrasound imaging system.Photoacoustics · 2021Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ultrasound imaging is widely used to guide minimally invasive procedures, but the visualization of the invasive medical device and the procedure’s target is often challenging. Photoacoustic imaging has shown great promise for guiding minimally invasive procedures, but clinical translation of this technology has often been limited by bulky and expensive excitation sources. In this work, we demonstrate the feasibility of guiding minimally invasive procedures using a dual-mode photoacoustic and ultrasound imaging system with excitation from compact arrays of light-emitting diodes (LEDs) at 850 nm. Three validation experiments were performed. First, clinical metal needles inserted into biological tissue were imaged. Second, the imaging depth of the system was characterized using a blood-vessel-mimicking phantom. Third, the superficial vasculature in human volunteers was imaged. It was found that photoacoustic imaging enabled needle visualization with signal-to-noise ratios that were 1.2 to 2.2 times higher than those obtained with ultrasound imaging, over insertion angles of 26 to 51 degrees. With the blood vessel mimicking phantom, the maximum imaging depth was 38 mm. The superficial vasculature of a human middle finger and a human wrist were clearly visualized in real-time. We conclude that the LED-based system is promising for guiding minimally invasive procedures with peripheral tissue targets.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.