Evidence map›Paper›PMID 29724002›Full record

ArticleMolecules (Basel, Switzerland)2018

Synthesis of New Benzothiazole Acylhydrazones as Anticancer Agents.

Derya Osmaniye, Serkan Levent, Abdullah Burak Karaduman, Sinem Ilgın, Yusuf Özkay, Zafer Asım Kaplancıklı

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 81 citations in OpenAlex.

  1. Article
  2. Article
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  4. Molecular engineering of multifunctional benzothiazole-sulfonamide hybrids: from synthesis to optoelectronic applications.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Acylhydrazones and Their Biological Activity: A Review.Molecules (Basel, Switzerland) · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Novel Isoniazid-Carborane Hybrids Active in Vitro AgainstPharmaceuticals (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Derya OsmaniyeDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. dosmaniye@anadolu.edu.tr.
Serkan LeventDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. serkanlevent@anadolu.edu.tr.
Abdullah Burak KaradumanDepartment of Pharmaceutical Toxicology, Faculty of Pharmacy, Anadolu Universty, 26470 Eskişehir, Turkey. abkaraduman@anadolu.edu.tr.
Sinem IlgınDepartment of Pharmaceutical Toxicology, Faculty of Pharmacy, Anadolu Universty, 26470 Eskişehir, Turkey. silgin@anadolu.edu.tr.
Yusuf ÖzkayDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. yozkay@anadolu.edu.tr.ORCID 0000-0001-8815-153X
Zafer Asım KaplancıklıDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. zakaplan@anadolu.edu.tr.ORCID 0000-0003-2252-0923
Anadolu University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the last five decades, a large number of BT (Benzothiazole) derivatives formed one of the eligible structures in medicinal chemistry as anticancer agents. Most of the studies reveal that various substitutions at specific positions on BT scaffold modulate the antitumor property. The potential of BTs encouraged us to synthesize a number of new 2-((5-substitutedbenzothiazol-2-yl)thio)-

Indexed as

Antineoplastic AgentsHydrazonesA549 CellsAnimalsHumansMCF-7 CellsMiceNeoplasmsNIH 3T3 CellsRatsAntineoplastic AgentsHydrazonesA549anticancerapoptosisbenzothiazoleC6HT-29hydrazoneMCF-7

Identifiers

PMID29724002
PMCPMC6102592
OpenAlexW2800353007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.