Evidence map›Paper›PMID 29723951›Full record

ArticleToxins2018

Pharmacological Cyclophilin Inhibitors Prevent Intoxication of Mammalian Cells with

Katharina Ernst, Nina Eberhardt, Ann-Katrin Mittler, Michael Sonnabend, Anna Anastasia, Simon Freisinger, Cordelia Schiene-Fischer, Miroslav Malešević, Holger Barth

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Review
  3. An endogenous human peptide derived from αNaunyn-Schmiedeberg's archives of pharmacology · 2026
    Article
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  5. Article
  6. Review
  7. Article
  8. Article
  9. Domperidone InhibitsToxins · 2023
    Article
  10. Article
  11. Article
  12. Crystal structures of pertussis toxin with NADThe Journal of biological chemistry · 2022
    Article
  13. Review
  14. Review
  15. International journal of molecular sciences · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Proline Isomerization as a Key Determinant for Hsp90-Toxin Interactions.Frontiers in cellular and infection microbiology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Katharina ErnstInstitute of Pharmacology and Toxicology, University of Ulm Medical Center, 89081 Ulm, Germany. katharina.ernst@uni-ulm.de.
Nina EberhardtInstitute of Pharmacology and Toxicology, University of Ulm Medical Center, 89081 Ulm, Germany. nina.eberhardt@uni-ulm.de.
Ann-Katrin MittlerInstitute of Pharmacology and Toxicology, University of Ulm Medical Center, 89081 Ulm, Germany. ann-katrin.mittler@uni-ulm.de.
Michael SonnabendInstitute of Pharmacology and Toxicology, University of Ulm Medical Center, 89081 Ulm, Germany. michael.sonnabend@web.de.
Anna AnastasiaInstitute of Pharmacology and Toxicology, University of Ulm Medical Center, 89081 Ulm, Germany. anna.anastasia@uni-ulm.de.
Simon FreisingerInstitute of Pharmacology and Toxicology, University of Ulm Medical Center, 89081 Ulm, Germany. simon.freisinger@uni-ulm.de.
Cordelia Schiene-FischerInstitute for Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. schiene@enzyme-halle.mpg.de.
Miroslav MaleševićInstitute for Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. miroslavmalesevic1@gmail.com.
Holger BarthInstitute of Pharmacology and Toxicology, University of Ulm Medical Center, 89081 Ulm, Germany. holger.barth@uni-ulm.de.
Universität Ulm · DEMartin Luther University Halle-Wittenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The

Indexed as

AnimalsBordetella pertussisCHO CellsCricetulusCyclophilinsCyclosporinePertussis ToxinProtein TransportRecombinant ProteinsCyclophilinsCyclosporinePertussis ToxinRecombinant Proteinscellular uptakechaperonescyclophilinscyclosporine Amembrane transportnovel drug targetspertussis toxinwhooping cough

Identifiers

PMID29723951
PMCPMC5983237
OpenAlexW2802350366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.