Evidence map›Paper›PMID 29722974›Full record

ArticleJournal of the American Chemical Society2018

Versatile Histochemical Approach to Detection of Hydrogen Peroxide in Cells and Tissues Based on Puromycin Staining.

Clive Yik-Sham Chung, Greg A Timblin, Kaoru Saijo, Christopher J Chang

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
8.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 106 citations in OpenAlex.

  1. Review
  2. A histochemical approach to activity-based copper sensing reveals cuproplasia-dependent vulnerabilities in cancer.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. A tandem activity-based sensing and labeling strategy enables imaging of transcellular hydrogen peroxide signaling.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  14. Article
  15. Bioresponsive drug delivery systems for the treatment of inflammatory diseases.Journal of controlled release : official journal of the Controlled Release Society · 2020
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Chemical science · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Clive Yik-Sham Chung
Greg A Timblin
Kaoru Saijo
Christopher J ChangORCID 0000-0001-5732-9497
University of California, Berkeley · USHoward Hughes Medical Institute · US

Funding

Training CoreP42ES004705 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI MORELLO-FROSCH, RACHEL ADELE · 1987 to 2025
$74.6M
Molecular Imaging Probes To Study Redox BiologyR01GM079465 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Christopher J. Chang · 2006 to 2026
$7.8M
Howard Hughes Medical InstituteNIEHS NIH HHS P42 ES004705NIGMS NIH HHS R01 GM079465
6 · The paper itself

Abstract

Hydrogen peroxide (H

Indexed as

AnimalsDiet, High-FatFluorescent DyesHeLa CellsHistocytochemistryHumansHydrogen PeroxideMaleMiceMice, Inbred C57BLMicroscopy, ConfocalMolecular StructureNon-alcoholic Fatty Liver DiseasePuromycinStaining and LabelingTumor Cells, CulturedFluorescent DyesHydrogen Peroxideperoxymycin-1Puromycin

Identifiers

PMID29722974
PMCPMC6069982
OpenAlexW2800600645

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.