ArticleBioinformatics (Oxford, England)2018
Modeling one thousand intron length distributions with fitild.
Article in Bioinformatics (Oxford, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Eukan: a fully automated nuclear genome annotation pipeline for less studied and divergent eukaryotes.NAR genomics and bioinformatics · 2026Article
- Phylogenetic Analysis of 590 Species Reveals Distinct Evolutionary Patterns of Intron-Exon Gene Structures Across Eukaryotic Lineages.Molecular biology and evolution · 2024Article
- GINGER: an integrated method for high-accuracy prediction of gene structure in higher eukaryotes at the gene and exon level.DNA research : an international journal for rapid publication of reports on genes and genomes · 2023Article
- The evolutionary dynamics that retain long neutral genomic sequences in face of indel deletion bias: a model and its application to human introns.Open biology · 2022Article
- A genetic screen in C. elegans reveals roles for KIN17 and PRCC in maintaining 5' splice site identity.PLoS genetics · 2022Article
- Cooperation of Spaln and Prrn5 for Construction of Gene-Structure-Aware Multiple Sequence Alignment.Methods in molecular biology (Clifton, N.J.) · 2021Article
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1 author.
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Abstract
Motivation: Intron length distribution (ILD) is a specific feature of a genome that exhibits extensive species-specific variation. Whereas ILD contributes to up to 30% of the total information content for intron recognition in some species, rendering it an important component of computational gene prediction, very few studies have been conducted to quantitatively characterize ILDs of various species. Results: We developed a set of computer programs (fitild, compild, etc.) to build statistical models of ILDs and compare them with one another. Each ILD of more than 1000 genomes was fitted with fitild to a statistical model consisting of one, two, or three components of Frechet distributions. Several measures of distances between ILDs were calculated by compild. A theoretical model was presented to better understand the origin of the observed shape of an ILD. Availability and implementation: The C++ source codes are available at https://github.com/ogotoh/fitild.git/. Supplementary information: Supplementary data are available at Bioinformatics online.
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