ArticleJournal of experimental botany2018
Glutathione modulates the expression of heat shock proteins via the transcription factors BZIP10 and MYB21 in Arabidopsis.
Article in Journal of experimental botany, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 55 citations in OpenAlex.
- Article
- Strigolactone-mediated drought tolerance in maize (Zea mays) seedlings: an omics approach.BMC plant biology · 2026Article
- Cysteine-mediated modulation of the glyoxalase system and HSP90 proteins enhances high-temperature stress tolerance inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2026Article
- Adapting Crops to Rising Temperatures: Understanding Heat Stress and Plant Resilience Mechanisms.International journal of molecular sciences · 2025Review
- Morphological and Transcriptomic Response Mediated by Heat Stress in Pleurotus Pulmonarius.Current microbiology · 2025Article
- Genome-Wide Identification and Evolution-Profiling Analysis ofInternational journal of molecular sciences · 2025Article
- Glutathione S-transferaseFrontiers in plant science · 2025Article
- Insights into the Heat Shock Protein 70 (Hsp70) Family inPlants (Basel, Switzerland) · 2024Article
- Article
- Wheat bZIPC1 interacts with FT2 and contributes to the regulation of spikelet number per spike.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- A LlMYB305-LlC3H18-LlWRKY33 module regulates thermotolerance in lily.Molecular horticulture · 2023Article
- The Functional Interplay between Ethylene, Hydrogen Sulfide, and Sulfur in Plant Heat Stress Tolerance.Biomolecules · 2022Review
- Interactome of Arabidopsis Thaliana.Plants (Basel, Switzerland) · 2022Article
- Transcriptomic analysis of COFrontiers in plant science · 2022Article
- Transcriptomic and Physiological Response of Durum Wheat Grain to Short-Term Heat Stress during Early Grain Filling.Plants (Basel, Switzerland) · 2021Article
- Effect of heat stress on oxidative damage and antioxidant defense system in white clover (Trifolium repens L.).Planta · 2021Article
- Genome-Wide Association Mapping and Gene Expression Analysis Reveal the Negative Role of OsMYB21 in Regulating Bacterial Blight Resistance in Rice.Rice (New York, N.Y.) · 2021Article
- Ecometabolomics for a Better Understanding of Plant Responses and Acclimation to Abiotic Factors Linked to Global Change.Metabolites · 2020Review
- Heterologous Expression of a Soybean GenePlants (Basel, Switzerland) · 2020Article
- The chromatin remodeler ZmCHB101 impacts alternative splicing contexts in response to osmotic stress.Plant cell reports · 2019Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The contribution of glutathione (GSH) in combating environmental stress in plants has long been known. Previous reports have pointed to the involvement of GSH in inducing various heat shock proteins (HSPs), but the molecular mechanism is yet to be explored. Here, we investigate how GSH induces the expression of important HSP genes in Arabidopsis. Expression of HSP genes BiP3, HSP70B, and HSP90.1 was positively regulated by GSH, and a promoter activation assay suggested a role for GSH in their induction. Lower expression of BiP3 and HSP70B in the GSH-fed Atmyb21 mutant and of HSP90.1 in the GSH-fed Atbzip10 mutant, in comparison with GSH-fed Col-0, revealed a role for GSH in activating their promoters through the transcription factors MYB21 and BZIP10. Co-transfection of transcription factor mutant protoplasts with transcription factor constructs and HSP promoters confirmed the results. Comparative proteomics also revealed proteins whose expression was controlled by MYB21 and BZIP10 in response to GSH feeding. A co-immunoprecipitation assay demonstrated a role for GSH in modulating the level of interaction of glutathione-S-transferase with HSP70. Collectively, our results demonstrate a role for GSH in activating the promoters of BiP3 and HSP70B via MYB21 and of HSP90.1 via BZIP10.
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