Evidence map›Paper›PMID 29722807›Full record

ArticleBioinformatics (Oxford, England)2018

The UEA sRNA Workbench (version 4.4): a comprehensive suite of tools for analyzing miRNAs and sRNAs.

Matthew B Stocks, Irina Mohorianu, Matthew Beckers, Claudia Paicu, Simon Moxon, Joshua Thody, Tamas Dalmay, Vincent Moulton

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Regulatory Landscapes of Non-Coding RNAs During Drought Stress in Plants.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matthew B StocksSchool of Computing Sciences, University of East Anglia, Norwich Research Park, Norwich, UK.
Irina MohorianuSchool of Computing Sciences, University of East Anglia, Norwich Research Park, Norwich, UK.
Matthew BeckersSchool of Computing Sciences, University of East Anglia, Norwich Research Park, Norwich, UK.
Claudia PaicuSchool of Computing Sciences, University of East Anglia, Norwich Research Park, Norwich, UK.
Simon MoxonSchool of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, UK.
Joshua ThodySchool of Computing Sciences, University of East Anglia, Norwich Research Park, Norwich, UK.
Tamas DalmaySchool of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, UK.
Vincent MoultonSchool of Computing Sciences, University of East Anglia, Norwich Research Park, Norwich, UK.

Funding

Biotechnology and Biological Sciences Research Council BB/L021269/1
6 · The paper itself

Abstract

Motivation: RNA interference, a highly conserved regulatory mechanism, is mediated via small RNAs (sRNA). Recent technical advances enabled the analysis of larger, complex datasets and the investigation of microRNAs and the less known small interfering RNAs. However, the size and intricacy of current data requires a comprehensive set of tools, able to discriminate the patterns from the low-level, noise-like, variation; numerous and varied suggestions from the community represent an invaluable source of ideas for future tools, the ability of the community to contribute to this software is essential. Results: We present a new version of the UEA sRNA Workbench, reconfigured to allow an easy insertion of new tools/workflows. In its released form, it comprises of a suite of tools in a user-friendly environment, with enhanced capabilities for a comprehensive processing of sRNA-seq data e.g. tools for an accurate prediction of sRNA loci (CoLIde) and miRNA loci (miRCat2), as well as workflows to guide the users through common steps such as quality checking of the input data, normalization of abundances or detection of differential expression represent the first step in sRNA-seq analyses. Availability and implementation: The UEA sRNA Workbench is available at: http://srna-workbench.cmp.uea.ac.uk. The source code is available at: https://github.com/sRNAworkbenchuea/UEA_sRNA_Workbench. Supplementary information: Supplementary data are available at Bioinformatics online.

Indexed as

SoftwareMicroRNAsRNA InterferenceRNA, Small InterferingSequence Analysis, RNAWorkflowMicroRNAsRNA, Small Interfering

Identifiers

PMID29722807
PMCPMC6157081

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.