Evidence map›Paper›PMID 29722339›Full record

ArticleChinese medical journal2018

Effect of Long-Term Systolic Blood Pressure Trajectory on Kidney Damage in the Diabetic Population: A Prospective Study in a Community-Based Chinese Cohort.

Jian-Chao Li, Jun Tian, Shou-Ling Wu, Zhi-Jun Wang, Xiao-Fei Zhang, Dao Jia, Rong-Jing Ding, Xiong-Fu Xiao, Yu-Bo Fan, Da-Yi Hu

Open access · goldAbstract read
In one paragraph

Article in Chinese medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Sex-specific medication trajectories in older adults newly diagnosed with diabetes.Exploratory research in clinical and social pharmacy · 2023
    Article
  2. Review
  3. Effect of blood pressure trajectory and variability on new-onset chronic kidney disease in patients with type 2 diabetes.Hypertension research : official journal of the Japanese Society of Hypertension · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jian-Chao LiSchool of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China.
Jun TianDepartment of Cardiology, Affiliated Hospital of North China University of Science and Technology, Tangshan, Hebei 063004, China.
Shou-Ling WuDepartment of Cardiology, Kailuan Hospital Affiliated to North China University of Science and Technology, Tangshan, Hebei 063001, China.
Zhi-Jun WangDepartment of Cardiology, Affiliated Hospital of North China University of Science and Technology, Tangshan, Hebei 063004, China.
Xiao-Fei ZhangDepartment of Clinical Epidemiology and Biostatistics, Beijing Tsinghua Changgung Hospital, Beijing 102218, China.
Dao JiaDepartment of Cardiology, Affiliated Hospital of North China University of Science and Technology, Tangshan, Hebei 063004, China.
Rong-Jing DingDepartment of Cardiology, Peking University People's Hospital, Beijing 100044, China.
Xiong-Fu XiaoSchool of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China.
Yu-Bo FanSchool of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China.
Da-Yi HuDepartment of Cardiology, Peking University People's Hospital, Beijing 100044, China.
North China University of Science and Technology · CNBeihang University · CNPeking University People's Hospital · CNBeijing Tsinghua Chang Gung Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies have shown that hypertension is an important factor contributing to the occurrence and progression of diabetic kidney damage. However, the relationship between the patterns of blood pressure (BP) trajectory and kidney damage in the diabetic population remains unclear. This prospective study investigated the effect of long-term systolic BP (SBP) trajectory on kidney damage in the diabetic population based on an 8-year follow-up community-based cohort.

methodsThis study included 4556 diabetic participants among 101,510 participants. BP, estimated glomerular filtration rate (eGFR), and urinary protein were measured every 2 years from 2006 to 2014. SBP trajectory was identified by the censored normal modeling. Five discrete SBP trajectories were identified according to SBP range and the changing pattern over time. Kidney damage was evaluated through eGFR and urinary protein value. A multivariate logistic regression model was used to analyze the influence of different SBP trajectory groups on kidney damage.

resultsWe identified five discrete SBP trajectories: low-stable group (n = 864), moderate-stable group (n = 1980), moderate increasing group (n = 609), elevated decreasing group, (n = 679), and elevated stable group (n = 424). The detection rate of kidney damage in the low-stable group (SBP: 118-124 mmHg) was the lowest among the five groups. The detection rate of each kidney damage index was higher in the elevated stable group (SBP: 159-172 mmHg) compared with the low-stable group. For details, the gap was 4.14 (11.6% vs. 2.8%) in eGFR <60 ml·min

conclusionAn elevated stable SBP trajectory is an independent risk factor for kidney damage in the diabetic population.

Indexed as

Asian PeopleBlood PressureFemaleGlomerular Filtration RateHumansHypertensionLogistic ModelsMaleProspective StudiesRisk FactorsBlood Pressure TrajectoryDiabetes with HypertensionKidney DamageLongitudinal DataTrajectory Model

Identifiers

PMID29722339
PMCPMC5956771
OpenAlexW2801353813

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.