Evidence map›Paper›PMID 29722126›Full record

ArticleNeurogastroenterology and motility2018

Reproducibility of gastric emptying assessed with scintigraphy in patients with upper GI symptoms.

A Desai, M O'Connor, B Neja, K Delaney, M Camilleri, A R Zinsmeister, A E Bharucha

Open access · greenAbstract read
In one paragraph

Article in Neurogastroenterology and motility, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 50 citations in OpenAlex.

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  10. Utility of aNeurogastroenterology and motility · 2025
    Article
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  15. Gastroparesis.Gastroenterology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

A DesaiDivision of Gastroenterology and Hepatology, Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.) Program, Mayo Clinic, Rochester, MN, USA.
M O'ConnorDivision of Nuclear Medicine, Department of Radiology, Mayo Clinic, Rochester, MN, USA.
B NejaDivision of Gastroenterology and Hepatology, Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.) Program, Mayo Clinic, Rochester, MN, USA.
K DelaneyDivision of Nuclear Medicine, Department of Radiology, Mayo Clinic, Rochester, MN, USA.
M CamilleriDivision of Gastroenterology and Hepatology, Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.) Program, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0001-6472-7514
A R ZinsmeisterDivision of Biostatistics, College of Medicine, Mayo Clinic, Rochester, MN, USA.
A E BharuchaDivision of Gastroenterology and Hepatology, Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.) Program, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-7644-0390
Mayo Clinic · US

Funding

Physiological Characterization and Data Integration CoreP01DK068055 · NIDDK · MAYO CLINIC ROCHESTER · PI FARRUGIA, GIANRICO · 2004 to 2019
$23.8M
NIDDK NIH HHS P01 DK068055USPHS NIH R01 DK068055
6 · The paper itself

Abstract

backgroundThe reproducibility of gastric emptying (GE) measured with scintigraphy in patients is poorly understood. Our aims were to assess the intra and inter-individual reproducibility of these parameters in patients with upper gastrointestinal symptoms.

methodsSixty patients (21 diabetics, 39 non-diabetics) with upper gastrointestinal symptoms underwent scintigraphic-assessment of GE of a solid meal (296 kcal, 30% fat) over 4 hours on two occasions at an average interval of 15 days. The concordance correlation coefficient (CCC), intra and inter-individual coefficients of variation (COV) of GE endpoints were analyzed.

resultsThe GE t CONCLUSIONS & INFERENCES: Among patients with upper gastrointestinal symptoms, GE measured with scintigraphy is relatively reproducible. In 30% of cases, the interpretation was different between the two assessments. Hence, a diagnosis of gastroparesis based on a single study may occasionally be inaccurate.

Indexed as

AdolescentAdultAgedAged, 80 and overFemaleGastric EmptyingGastroparesisHumansMaleMiddle AgedRadionuclide ImagingReproducibility of ResultsYoung Adultdiabetes mellitusgastric emptyinggastroparesisreproducibilityscintigraphy

Identifiers

PMID29722126
PMCPMC6160344
OpenAlexW2800278196

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.