Evidence map›Paper›PMID 29721773›Full record

ArticleDigestive diseases and sciences2018

Prolonged Cecal Insertion Time Is Not Associated with Decreased Adenoma Detection When a Longer Withdrawal Time Is Achieved.

Cassandra D L Fritz, Zachary L Smith, Jeffrey Elsner, Thomas Hollander, Dayna Early, Vladimir Kushnir

Registry-linked trialAbstract read
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In one paragraph

Article in Digestive diseases and sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05422820 (The Argentina Brief Colonoscopy Difficulty Score), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05422820 completednot on this mapstarted 2022, after this paper: background citation

The Argentina Brief Colonoscopy Difficulty Score (ABCD): A Novel Tool to Estimate the Technical Difficulty of Colonoscopy With Caecal Intubation

Typeobservational_patient_registrySponsorInstitute of Gastroenterology and Advance EndoscopyRan2022 to 2023Enrolled5,000ConditionsColorectal Cancer, Diagnoses Disease, Polyp of Colon, Adenoma ColonArmsDiagnostic high-definition white-light (HDWL) colonoscopy
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Negative effect of prolonged cecal intubation time on adenoma detection in female patients.JGH open : an open access journal of gastroenterology and hepatology · 2023
    Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Cassandra D L FritzBarnes Jewish Hospital, Washington University, St. Louis, MO, USA.
Zachary L SmithDivision of Gastroenterology, Washington University, 660 S. Euclid Avenue, Campus Box 8124, St. Louis, MO, USA.
Jeffrey ElsnerDivision of Gastroenterology, Washington University, 660 S. Euclid Avenue, Campus Box 8124, St. Louis, MO, USA.
Thomas HollanderDivision of Gastroenterology, Washington University, 660 S. Euclid Avenue, Campus Box 8124, St. Louis, MO, USA.
Dayna EarlyDivision of Gastroenterology, Washington University, 660 S. Euclid Avenue, Campus Box 8124, St. Louis, MO, USA.
Vladimir KushnirDivision of Gastroenterology, Washington University, 660 S. Euclid Avenue, Campus Box 8124, St. Louis, MO, USA. vkushnir@wustl.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe association between withdrawal time and adenoma detection has been established; however, the effect of cecal insertion time on adenoma detection remains unclear.

aimTo determine the association between cecal insertion time and adenoma detection.

methodsThis study completed a retrospective analysis of data collected in 4 prospective randomized-controlled trials related to screening and surveillance colonoscopy at a single tertiary care from 2010 to 2016. The primary outcome was cecal insertion time and its association with mean number of adenomas per patient and adenoma detection rate (ADR).

results1303 patients met inclusion criteria (average age 59.7 ± 8.7 years; 759 females (58.3%), and 763 Caucasians (58.6%). Mean cecal insertion time was significantly longer in patients who were female (p < 0.001), received moderate sedation (p = 0.001), had fellow involvement (p < 0.001), older (p = 0.002), and lower Boston bowel preparation scale (p < 0.001). Withdrawal time was found to increase as mean cecal insertion time increased (p < 0.001). The mean cecal insertion time was not different in patients with or without adenomas (p = 0.94). Cecal insertion time did not correlate with the mean number of adenomas or advanced adenomas per patient (p > 0.05), which was also true on Poisson regression analysis. Adenomas and advanced adenomas per patient were found to decrease when cecal insertion to withdrawal time ratios were greater than 1 (p < 0.001).

conclusionsProlonged cecal insertion time was not associated with a decrease in ADR, mean number of adenomas or advanced adenomas per patient. When withdrawal times were longer than cecal insertion times, the number of adenomas and advanced adenomas detected per patient was significantly improved.

Indexed as

AdenomaAgedColonic NeoplasmsColonoscopyFemaleHumansMaleMiddle AgedRandomized Controlled Trials as TopicRetrospective StudiesTime FactorsAdenoma detectionCecal insertion timeColorectal cancer preventionScreening colonoscopyWithdrawal time

Identifiers

PMID29721773

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Registered trials

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