Evidence map›Paper›PMID 29721766›Full record

ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2018

Radiotherapy volume delineation using 18F-FDG-PET/CT modifies gross node volume in patients with oesophageal cancer.

E Jimenez-Jimenez, P Mateos, N Aymar, R Roncero, I Ortiz, M Gimenez, J Pardo, J Salinas, S Sabater

Abstract readComparative StudyEvaluation Study
PubMed Publisher
In one paragraph

Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Diagnosis and prognostic predictive value of delineation methods fromAmerican journal of nuclear medicine and molecular imaging · 2023
    Article
  5. Article
  6. Impact ofStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020
    Article
  7. Recent advances of PET imaging in clinical radiation oncology.Radiation oncology (London, England) · 2020
    Review
  8. Nodal FDG-PET/CT uptake influences outcome and relapse location among esophageal cancer patients submitted to chemotherapy or radiochemotherapy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2019
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

E Jimenez-JimenezRadiation Oncology Department, St. Lucia University General Hospital, Cartagena, Spain. estherjj83@gmail.com.ORCID http://orcid.org/0000-0003-1170-1702
P MateosMedical Physics Department, Clinica IMQ Zorrotzaurre, Bilbao, Spain.
N AymarRadiation Oncology Department, Hospital Universitari Son Espases, Palma de Mallorca, Spain.
R RonceroRadiation Oncology Department, Hospital Universitari Son Espases, Palma de Mallorca, Spain.
I OrtizRadiation Oncology Department, Hospital Universitari Son Espases, Palma de Mallorca, Spain.
M GimenezNuclear Medicine Department, Hospital Universitari Son Espases, Palma de Mallorca, Spain.
J PardoRadiation Oncology Department, Hospital Universitari Son Espases, Palma de Mallorca, Spain.
J SalinasRadiation Oncology Department, St. Lucia University General Hospital, Cartagena, Spain.
S SabaterRadiation Oncology Department, Complejo Hospitalario Universitario de Albacete, Albacete, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEvidence supporting the use of 18F-FDG-PET/CT in the segmentation process of oesophageal cancer for radiotherapy planning is limited. Our aim was to compare the volumes and tumour lengths defined by fused PET/CT vs. CT simulation. MATERIALS AND

methodsTwenty-nine patients were analyzed. All patients underwent a single PET/CT simulation scan. Two separate GTVs were defined: one based on CT data alone and another based on fused PET/CT data. Volume sizes for both data sets were compared and the spatial overlap was assessed by the Dice similarity coefficient (DSC).

resultsThe gross tumour volume (GTVtumour) and maximum tumour diameter were greater by PET/CT, and length of primary tumour was greater by CT, but differences were not statistically significant. However, the gross node volume (GTVnode) was significantly greater by PET/CT. The DSC analysis showed excellent agreement for GTVtumour, 0.72, but was very low for GTVnode, 0.25.

conclusionsOur study shows that the volume definition by PET/CT and CT data differs. CT simulation, without taking into account PET/CT information, might leave cancer-involved nodes out of the radiotherapy-delineated volumes.

Indexed as

Fluorodeoxyglucose F18Tumor BurdenAgedAged, 80 and overCarcinoma, Squamous CellChemoradiotherapyEsophageal NeoplasmsFemaleHumansMaleMiddle AgedPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadiotherapy Planning, Computer-AssistedRetrospective StudiesFluorodeoxyglucose F1818F-FDG-PET/CTDelineationOesophagealRadiotherapy

Identifiers

PMID29721766

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.