ArticleClinical research in cardiology : official journal of the German Cardiac Society2018
Cardiac autonomic modulation impairments in advanced breast cancer patients.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed, 29 citations in OpenAlex.
- Long-term effects of device-guided slow breathing in stable heart failure patients with reduced ejection fraction.Clinical research in cardiology : official journal of the German Cardiac Society · 2019Trial
- Key role of the autonomic nervous system in breast cancer (Review).Experimental and therapeutic medicine · 2026Review
- Association of Sympathovagal Imbalance with Increased Inflammation and Impaired Adaptive Immunity in Bladder Cancer Patients.International journal of molecular sciences · 2024Article
- Increased stress burden and electrodermal reactivity in bladder cancer patients in comparison to healthy controls.Heliyon · 2024Article
- Long-Term Prognostic Value ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023Article
- Effects of Ballistocardiogram Peak Detection Jitters on the Quality of Heart Rate Variability Features: A Simulation-Based Case Study in the Context of Sleep Staging.Sensors (Basel, Switzerland) · 2023Article
- Exploring autonomic modulation: day-to-day recovery after exercise sessions in breast cancer survivors.Frontiers in oncology · 2023Article
- Diagnostic role of heart rate variability in breast cancer and its relationship with peripheral serum carcinoembryonic antigen.PloS one · 2023Article
- Increased sympathetic modulation in breast cancer survivors determined by measurement of heart rate variability.Scientific reports · 2022Article
- Differences in the Impact of Heart Rate Variability on the Surgical Approach in Patients With Early Cervical Cancer: Laparoscopic versus Open Surgery.Frontiers in oncology · 2022Article
- Low Heart Rate Variability Predicts Poor Overall Survival of Lung Cancer Patients With Brain Metastases.Frontiers in neuroscience · 2022Article
- Relationship between Heart Rate Variability and Functional Fitness in Breast Cancer Survivors: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2021Article
- Association between short-term heart rate variability and blood coagulation in patients with breast cancer.Scientific reports · 2021Article
- Heart Rate Variability is an Independent Predictor of Lymph Node Metastasis in Patients with Cervical Cancer.Cancer management and research · 2021Article
- Association of Short-Term Heart Rate Variability With Breast Tumor Stage.Frontiers in physiology · 2021Article
- FIFA World Cup 2018: effect of emotional stress on conventional heart rate variability metrics.Clinical research in cardiology : official journal of the German Cardiac Society · 2020Article
- The role of heart rate in the assessment of cardiac autonomic modulation with heart rate variability.Clinical research in cardiology : official journal of the German Cardiac Society · 2019Article
- Reply to the letter "The role of heart rate in the assessment of cardiac autonomic modulation with heart rate variability".Clinical research in cardiology : official journal of the German Cardiac Society · 2019Article
- Epicardial fat accumulation is an independent marker of impaired heart rate recovery in obese patients with obstructive sleep apnea.Clinical research in cardiology : official journal of the German Cardiac Society · 2019Article
- Doxorubicin treatments induce significant changes on the cardiac autonomic nervous system in childhood acute lymphoblastic leukemia long-term survivors.Clinical research in cardiology : official journal of the German Cardiac Society · 2019Article
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Authors and funding
11 authors at 7 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo compare cardiac autonomic modulation in early- versus advanced-stage breast cancer patients before any type of cancer treatment and investigate associated factors. METHODS AND
resultsThis cross-sectional study included women (30-69 years old) with primary diagnosis of breast cancer and women with benign breast tumors. We evaluated cardiac modulation by heart rate variability and assessed factors of anxiety, depression, physical activity, and other relevant medical variables. Patients were divided into three groups based on TNM staging of cancer severity: early-stage cancer (n = 42), advanced-stage cancer (n = 37), or benign breast tumors to serve as a control (n = 37). We analyzed heart rate variability in time and frequency domains. The advanced-stage cancer group had lower vagal modulation than early-stage and benign groups; also, the advance-stage group had lower overall heart rate variability when compared to benign conditions. Heart rate variability was influenced by age, menopausal status, and BMI.
conclusionsHeart rate variability seems to be a promising, non-invasive tool for early diagnosis of autonomic dysfunction in breast cancer and detection of cardiovascular impairments at cancer diagnosis. Cardiac autonomic modulation is inversely associated with breast cancer staging.
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