Evidence map›Paper›PMID 29721529›Full record

ArticleACS central science2018

Mosquito-Derived Anophelin Sulfoproteins Are Potent Antithrombotics.

Emma E Watson, Xuyu Liu, Robert E Thompson, Jorge Ripoll-Rozada, Mike Wu, Imala Alwis, Alessandro Gori, Choy-Theng Loh, Benjamin L Parker, Gottfried Otting and 3 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS central science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 42 citations in OpenAlex.

  1. Discovery of a Reversible Sub-Picomolar Thrombin Inhibitor Using DCC.Angewandte Chemie (International ed. in English) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Functional cross-talk between phosphorylation and disease-causing mutations in the cardiac sodium channel NaProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  7. Article
  8. Review
  9. Semisynthesis of an evasin from tick saliva reveals a critical role of tyrosine sulfation for chemokine binding and inhibition.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Emma E WatsonSchool of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.
Xuyu LiuSchool of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.
Robert E ThompsonSchool of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.
Jorge Ripoll-RozadaIBMC - Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.
Mike WuHeart Research Institute, Newtown, New South Wales 2042, Australia.
Imala AlwisHeart Research Institute, Newtown, New South Wales 2042, Australia.
Alessandro GoriSchool of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.
Choy-Theng LohResearch School of Chemistry, Australian National University, Canberra, Australian Capital Territory 2601, Australia.
Benjamin L ParkerCharles Perkins Centre, The University of Sydney, Sydney, New South Wales 2006, Australia.
Gottfried OttingResearch School of Chemistry, Australian National University, Canberra, Australian Capital Territory 2601, Australia.
Shaun JacksonHeart Research Institute, Newtown, New South Wales 2042, Australia.
Pedro José Barbosa PereiraIBMC - Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.
Richard J PayneSchool of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.
The University of Sydney · AUAustralian National University · AUUniversidade do Porto · PTScripps Research Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anophelins are small protein thrombin inhibitors that are produced in the salivary glands of the

Identifiers

PMID29721529
PMCPMC5920608
OpenAlexW2794566115

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.