Evidence map›Paper›PMID 29721472›Full record

ArticleSouth Asian journal of cancer

Practical consensus recommendations on management of HR + ve early breast cancer with specific reference to genomic profiling.

S Aggarwal, A Vaid, A Ramesh, Purvish M Parikh, S Purohit, B Avasthi, S Gupta, S Ranjan, V Kaushal, S Salim and 3 more

Open access · diamondAbstract read
In one paragraph

Article in South Asian journal of cancer. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 2 countries.

S AggarwalDepartment of Medical Oncology, Sir Ganga Ram Hospital, New Delhi, India.
A VaidDepartment of Medical Oncology, Medanata Hospital, Gurugram, Haryana, India.
A RameshDepartment of Medical Oncology, HCG Cancer Center, Chennai, Tamil Nadu, India.
Purvish M ParikhDepartment of Oncology, Shalby Cancer and Research Institute, Mumbai, Maharashtra, India.
S PurohitDepartment of Medical Oncology, Artemis Hospital, Gurugram, Haryana, India.
B AvasthiDepartment or Radiation Oncology, Fortis Hospital, New Delhi, India.
S GuptaDepartment of Medical Oncology, Sarvodaya Hospital, Faridabad, Haryana, India.
S RanjanDepartment of Medicine, INHS Sanjivani, Kochi, Kerala, India.
V KaushalDepartment of Radiation Oncology, RCC, Rohtak, Haryana, India.
S SalimDepartment of Oncology, Hakim Sanaullah Cancer Center, Baramulla, Jammu and Kashmir, India.
R SinghDepartment of Medical Oncology, Army Hospital R and R, New Delhi, India.
S MinhasDepartment of Medical Oncology, Medanata Hospital, Gurugram, Haryana, India.
D DovalDepartment of Medical Oncology, Rajiv Gandhi Cancer Institute, New Delhi, India.
Army Hospital Research and Referral · INArtemis Hospitals · INFortis Hospital · INHCG Cancer Centre · ININHS Asvini · INRajiv Gandhi Cancer Institute and Research Centre · INShalby Hospitals · INSir Ganga Ram Hospital · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is a heterogeneous disease and patients are managed clinically based on ER, PR, HER2 expression, and key risk factors. The use of gene expression assays for early stage disease is already common practice. These tests have found a place in risk stratifying the heterogeneous group of stage I-II breast cancers for recurrence, for predicting chemotherapy response, and for predicting breast cancer-related mortality. Most guidelines for hormone receptor (HR)-positive early breast cancer recommend addition of adjuvant chemotherapy for most women, leading to overtreatment, which causes considerable morbidity and cost. Expert oncologist discussed about strategies of gene expression assays and aid in chemotherapy recommendations for treatment of HR + ve EBC and the expert group used data from published literature, practical experience and opinion of a large group of academic oncologists to arrive at this practical consensus recommendations for the benefit of community oncologists.

Indexed as

ki67mammaprintoncotype dxpredictive testprosignataxane

Identifiers

PMID29721472
PMCPMC5909304
OpenAlexW2796744928

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.