Evidence map›Paper›PMID 29721452›Full record

ArticleMuscles, ligaments and tendons journal

Finite element comparison between the human and the ovine lumbar intervertebral disc.

Gloria Casaroli, Tomaso Villa, Fabio Galbusera

Abstract read
In one paragraph

Article in Muscles, ligaments and tendons journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gloria CasaroliLaboratory of Biological Structures Mechanics, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Tomaso VillaLaboratory of Biological Structure Mechanics (LaBS), Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Milan, Italy.
Fabio GalbuseraLaboratory of Biological Structures Mechanics, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Istituto Ortopedico Galeazzi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNowadays it is still not clear which loading conditions are responsible for lumbar intervertebral disc failure. Many studies have been conducted to investigate the effect of different loading conditions on the herniation processes, and many of them were based on the ovine model. However, the biomechanical similarities between the human and the ovine lumbar disc have been demonstrated in the main planes only, whereas it is not known if they are comparable under complex loading conditions too. The aim of this study was to compare the mechanical response of the ovine and the human lumbar intervetebral disc under complex loading conditions, in order to investigate differences and similarities between the species.The loading scenarios described in a finite element study on a human lumbar segment were applied to a model of the ovine disc, and the results were then compared.It has been shown that combined loads generated highest strains in both the models, and the maximum strains had the same location in the posterior or in the postero-lateral region of the annulus, according to the loading scenario.

conclusionThe ovine disc can be used in spinal research to investigate herniation process under any loading conditions. LEVEL OF EVIDENCE: V.

Indexed as

animal modelanisotropic hyperelasticfinite element analysis

Identifiers

PMID29721452
PMCPMC5908327
OpenAlexW2800046458

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.