Evidence map›Paper›PMID 29721241›Full record

ArticleInfectious disease reports2018

Syphilis infection in an HIV patient presenting with leukemoid reaction: Case report and review of the literature.

Athina Lioni, Markela-Pagonitsa Zorzou, Christina Kollia, Dimitrios Loulakis, Fotini Ntziora, Fotini Stergiou, Maria Boboli, Maria Chini

Open access · goldAbstract read
In one paragraph

Article in Infectious disease reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Athina LioniInfectious Diseases Unit.
Markela-Pagonitsa ZorzouInfectious Diseases Unit.
Christina KolliaInternal Medicine Department Red Cross Hospital Korgialeneio Benakeio, Athens, Greece.
Dimitrios LoulakisInternal Medicine Department Red Cross Hospital Korgialeneio Benakeio, Athens, Greece.
Fotini NtzioraInfectious Diseases Unit.
Fotini StergiouInfectious Diseases Unit.
Maria BoboliInfectious Diseases Unit.
Maria ChiniInfectious Diseases Unit.
Hellenic Red Cross · GRRed Cross Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leukemoid reaction (LR) is an uncommon though dreadful sign for the treating physician, as it is related to increased mortality. In the few series that have addressed its incidence and clinical significance, infectious causes count for about half of the cases of LR, the rest accounting for cancer, drugs or rarer causes. In the HIV setting, it represents an even rarer event, owing probably to the impaired granulocytic response of AIDS patients to bacterial agents. However no report exists as to the incidence of LR to the immune-restored HIV patients adequately treated with antiretroviral therapy (ART). Syphilis is a well known cause of mild lymphocytosis, though only one report of LR exists in the congenital setting. We hereby report a case of an HIV patient adequately treated with ART, who presented with LR with a lymphomonocytic preponderance after infection with treponema pallidum.

Indexed as

HIVleukemoid reactionsyphilis

Identifiers

PMID29721241
PMCPMC5907733
OpenAlexW2796303993

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.